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Galina V. Ermakova

Researcher at Russian Academy of Sciences

Publications -  42
Citations -  2579

Galina V. Ermakova is an academic researcher from Russian Academy of Sciences. The author has contributed to research in topics: Xenopus & Homeobox. The author has an hindex of 19, co-authored 41 publications receiving 2378 citations.

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Bright far-red fluorescent protein for whole-body imaging.

TL;DR: A far-red fluorescent protein, named Katushka, is reported, which is seven- to tenfold brighter compared to the spectrally close HcRed or mPlum, and is characterized by fast maturation as well as a high pH-stability and photostability, which makes it the protein of choice for visualization in living tissues.
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"Fluorescent timer": protein that changes color with time.

TL;DR: In vivo labeling with E5 is used to measure expression from the heat shock-dependent promoter in Caenorhabditis elegans and from the Otx-2 promoter in developing Xenopus embryos to monitor both activation and down-regulation of target promoters on the whole-organism scale.
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The homeobox gene, Xanf-1, can control both neural differentiation and patterning in the presumptive anterior neurectoderm of the Xenopus laevis embryo.

TL;DR: It is demonstrated that ectopic Xanf-1 can expand the neural plate at expense of adjacent non-neural ectoderm, and data indicate that the repressor function of Xan f-1 may be necessary for regulation of both neural differentiation and patterning in the presumptive anterior neurectoderm.