G
Gamini Kumarasinghe
Researcher at National University of Singapore
Publications - 21
Citations - 987
Gamini Kumarasinghe is an academic researcher from National University of Singapore. The author has contributed to research in topics: Ampicillin & Methicillin-resistant Staphylococcus aureus. The author has an hindex of 14, co-authored 21 publications receiving 949 citations.
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Journal ArticleDOI
High prevalence of antimicrobial resistance among clinical Streptococcus pneumoniae isolates in Asia (an ANSORP study).
Jae-Hoon Song,Sook-In Jung,Kwan Soo Ko,Nayoung Kim,Jun Seong Son,Hyun-Ha Chang,Hyun Kyun Ki,Won Sup Oh,Ji Yoeun Suh,Kyong Ran Peck,Nam Yong Lee,Yonghong Yang,Quan Lu,Anan Chongthaleong,Cheng-Hsun Chiu,M. K. Lalitha,Jennifer Perera,Ti Teow Yee,Gamini Kumarasinghe,Farida Jamal,Adeeba Kamarulzaman,Parasakthi N,Pham Hung Van,Celia C. Carlos,Thomas Man-kit So,Tak Keung Ng,Atef M. Shibl +26 more
TL;DR: Multilocus sequence typing showed that the spread of the Taiwan19F clone and the Spain23F clone could be one of the major reasons for the rapid increases in antimicrobial resistance among S. pneumoniae isolates in Asia.
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High Rate of Reduced Susceptibility to Ciprofloxacin and Ceftriaxone among Nontyphoid Salmonella Clinical Isolates in Asia
Hao-Yuan Lee,Lin-Hui Su,Lin-Hui Su,Ming-Han Tsai,Ming-Han Tsai,Shin Woo Kim,Hyun-Ha Chang,Sook-In Jung,Kyung-Hwa Park,Jennifer Perera,Celia C. Carlos,Ban Hock Tan,Gamini Kumarasinghe,Thomas Man-kit So,Anan Chongthaleong,Po-Ren Hsueh,Jien-Wei Liu,Jae-Hoon Song,Cheng-Hsun Chiu,Cheng-Hsun Chiu +19 more
TL;DR: It was revealed that reduced susceptibility to ciprofloxacin in nontyphoid Salmonella isolates was common in Taiwan and Thailand, and in S. enterica serotype Choleraesuis and Virchow from all countries.
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Inhibition of Gene Expression and Growth by Antisense Peptide Nucleic Acids in a Multiresistant β-Lactamase-Producing Klebsiella pneumoniae Strain
TL;DR: Two antisense peptide nucleic acids conjugated to the (KFF)3K peptide were developed and investigated whether they could mediate gene-specific antisense effects in K. pneumoniae and specifically inhibited expression of DNA gyrase subunit A and OmpA from the respective targeted genes in a dose-dependent manner.
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Identification of vaccine candidate antigens of an ESBL producing Klebsiella pneumoniae clinical strain by immunoproteome analysis.
TL;DR: Two of the vaccine candidate genes, OmpA and FepA, have recently been shown to be essential in colonization and infection in an in vivo mouse model and could serve as potential vaccine candidates.
Journal Article
Antimicrobial susceptibility of Shigella isolates in eight Asian countries, 2001-2004
Chen-Yen Kuo,Lin-Hui Su,Jennifer Perera,Celia C. Carlos,Ban Hock Tan,Gamini Kumarasinghe,Thomas Man-kit So,Pham Hung Van,Anan Chongthaleong,Jae-Hoon Song,Cheng-Hsun Chiu +10 more
TL;DR: High rates of multidrug resistance and steady increases in ceftriaxone and ciprofloxacin resistance of Shigella are serious pubic health concerns in Asian countries.