G
Garth L. Nicolson
Researcher at University of Helsinki
Publications - 237
Citations - 23832
Garth L. Nicolson is an academic researcher from University of Helsinki. The author has contributed to research in topics: Cell culture & Membrane. The author has an hindex of 65, co-authored 228 publications receiving 23086 citations. Previous affiliations of Garth L. Nicolson include Salk Institute for Biological Studies & The New School.
Papers
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Journal ArticleDOI
The fluid mosaic model of the structure of cell membranes.
S. J. Singer,Garth L. Nicolson +1 more
TL;DR: Results strongly indicate that the bivalent antibodies produce an aggregation of the surface immunoglobulin molecules in the plane of the membrane, which can occur only if the immunoglOBulin molecules are free to diffuse in the membrane.
Book ChapterDOI
The interactions of lectins with animal cell surfaces.
TL;DR: This chapter discusses the interactions of lectins with animal cell surfaces, which have proven to be quite useful for clinical blood typing and structural studies of blood group substances, in analysis of the surface structure of normal and tumor cells, and so on.
Journal ArticleDOI
The Fluid—Mosaic Model of Membrane Structure: Still relevant to understanding the structure, function and dynamics of biological membranes after more than 40 years
TL;DR: In updated versions of the model more emphasis has been placed on the mosaic nature of the macrostructure of cellular membranes where many protein and lipid components are limited in their rotational and lateral motilities in the membrane plane, especially in their natural states.
Journal Article
Tumor cell instability, diversification, and progression to the metastatic phenotype: from oncogene to oncofetal expression
TL;DR: It is proposed that tumor cell instability and the expression of cellular diversification mechanisms ensure that malignant neoplasms contain heterogeneous, phenotypically diverse tumor cell subpopulations.
Journal ArticleDOI
The interaction of Ricinus communis agglutinin with normal and tumor cell surfaces.
Garth L. Nicolson,John Blaustein +1 more
TL;DR: The significance of the change in agglutinability of transformed or trypsinized cells is discussed in relation to the topology of the cell surface.