G
Garth L. Nicolson
Researcher at University of Helsinki
Publications - 237
Citations - 23832
Garth L. Nicolson is an academic researcher from University of Helsinki. The author has contributed to research in topics: Cell culture & Membrane. The author has an hindex of 65, co-authored 228 publications receiving 23086 citations. Previous affiliations of Garth L. Nicolson include Salk Institute for Biological Studies & The New School.
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ANIONIC SITES OF HUMAN ERYTHROCYTE MEMBRANES : I. Effects of Trypsin, Phospholipase C, and pH on the Topography of Bound Positively Charged Colloidal Particles
TL;DR: Investigation of the effects of pH, trypsin, and phospholipase C on the topographic distribution of acidic anionic residues on human erythrocytes found evidence that N -acetylneuraminic acid groups are the principal acidic residues binding colloidal iron.
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Tumor metastasis-associated human MTA1 gene and its MTA1 protein product: role in epithelial cancer cell invasion, proliferation and nuclear regulation.
Garth L. Nicolson,Akihiro Nawa,Yasushi Toh,Shigeki Taniguchi,Katsuhiko Nishimori,Amr S. Moustafa +5 more
TL;DR: The results suggest that the MTA1 protein may serve multiple functions in cellular signaling, chromosome remodeling and transcription processes that are important in the progression, invasion and growth of metastatic epithelial cells.
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Clonal Drift of Cell Surface, Melanogenic, and Experimental Metastatic Properties of in Vivo-selected, Brain Meninges-colonizing Murine B16 Melanoma
TL;DR: Examination of exposed cell surface proteins by lactoperoxidase-catalyzed 125I iodination and sodium dodecyl sulfate:polyacrylamide slab gel electrophoresis autoradiography revealed increased exposures of a component with an approximate molecular weight of 90,000 on B16 sublines and clones with high brain colonization potentials.
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Comparison of 'spontaneous' and 'experimental' metastasis using rat 13762 mammary adenocarcinoma metastatic cell clones.
TL;DR: Heterogeneity in tumor cell clonal metastatic potential is demonstrated in the 13762NF mammary adenocarcinoma system and ranking by average tumor burden calculated from total lung tumor volumes may yield a better estimate of metastasis potential than ranking by the average number of lung tumor colonies.
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Characterization of the Inhibitory Effects of Retinoids on the In Vitro Growth of Two Malignant Murine Melanomas
TL;DR: The in vitro proliferation of murine melanoma cell lines S91 and B16 was inhibited by retinoic acid and retinyl acetate, and both cell lines were more sensitive to retinooic acid than to retinylacetate.