G
Gary L. Wright
Researcher at East Tennessee State University
Publications - 86
Citations - 2225
Gary L. Wright is an academic researcher from East Tennessee State University. The author has contributed to research in topics: Calcium & Actin. The author has an hindex of 25, co-authored 86 publications receiving 2070 citations. Previous affiliations of Gary L. Wright include University of Missouri & Medical University of South Carolina.
Papers
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Journal ArticleDOI
Erythropoietin receptor expression in adult rat cardiomyocytes is associated with an acute cardioprotective effect for recombinant erythropoietin during ischemia-reperfusion injury.
Gary L. Wright,Paul R. Hanlon,Khalid Amin,Charles Steenbergen,Elizabeth Murphy,Murat O. Arcasoy +5 more
TL;DR: Experiments revealed that the rapid cardioprotective effect of EPO during ischemia‐reperfusion injury was associated with preservation of ATP levels in the ischemic myocardium.
Journal ArticleDOI
Mechanisms of erythropoietin-mediated cardioprotection during ischemia-reperfusion injury: role of protein kinase C and phosphatidylinositol 3-kinase signaling
TL;DR: It is shown that postischemia EPO treatment at the onset of reperfusion significantly improved recovery of LVDP and reduced infarct size and EPO‐mediated cardioprotection by EPO required the PI3K pathway but was not affected by inhibition of PKC at the time ofEPO treatment.
Journal ArticleDOI
VEGF stimulation of mitochondrial biogenesis: requirement of AKT3 kinase
Gary L. Wright,Ioanna G. Maroulakou,Juanita Eldridge,Tiera L. Liby,Vijayalakshmi Sridharan,Philip N. Tsichlis,Robin C. Muise-Helmericks +6 more
TL;DR: A subtle but significant, abnormal mitochondrial phenotype is observed in the brain tissue of AKT3 knockout mice, suggesting that Akt3 is important in coordinating mitochondrial biogenesis with growth factor‐induced increases in cellular energy demands.
Journal ArticleDOI
Endotoxin stress-response in cardiomyocytes: NF-κB activation and tumor necrosis factor-α expression
Gary L. Wright,Ishwar S. Singh,Jeffery D. Hasday,Iain K. Farrance,Gentzon Hall,Allan S. Cross,Terry B. Rogers +6 more
TL;DR: The intracellular events leading to its production by heart cells are largely unknown and TNF-α is implicated in numerous cardiac pathologies, but its role in these pathologies is largely unknown.
OtherDOI
C1q/TNF‐Related Protein 3 (CTRP3) Function and Regulation
TL;DR: A comprehensive overview of the research concerning the expression, regulation, and physiological function of CTRP3 is provided, highlighting profound biological potency of this adipokine family.