G
Gary S. Hoffman
Researcher at National Institutes of Health
Publications - 29
Citations - 10005
Gary S. Hoffman is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Vasculitis & Immunoreactive trypsinogen. The author has an hindex of 21, co-authored 28 publications receiving 8728 citations. Previous affiliations of Gary S. Hoffman include Johns Hopkins University & Cleveland Clinic.
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Journal ArticleDOI
2012 Revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides
John Charles Jennette,Ronald Falk,P. A. Bacon,Neil Basu,Maria C. Cid,Franco Ferrario,Luis Felipe Flores-Suárez,W. L. Gross,Loïc Guillevin,E. C. Hagen,Gary S. Hoffman,David Jayne,Cees G. M. Kallenberg,Peter Lamprecht,Carol A. Langford,Raashid Luqmani,Alfred Mahr,Eric L. Matteson,Peter A. Merkel,Peter A. Merkel,Seza Ozen,Charles D. Pusey,Niels Rasmussen,Andrew J. Rees,David G. I. Scott,Ulrich Specks,John H. Stone,Kei Takahashi,Richard A. Watts +28 more
TL;DR: 2012 Revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides J. Watts; Arthritis & Rheumatism
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Wegener granulomatosis : an analysis of 158 patients
Gary S. Hoffman,Gail S. Kerr,Randi Y. Leavitt,Claire W. Hallahan,Robert S. Lebovics,William D. Travis,Menachem Rottem,Anthony S. Fauci +7 more
TL;DR: The course of Wegener granulomatosis has been dramatically improved by daily treatment with cyclophosphamide and glucocorticoids, and has led to increasing concerns about toxicity resulting from prolonged cycloph phosphamide therapy and has encouraged investigation of other therapeutic regimens.
Journal ArticleDOI
Endothelins, peptides with potent vasoactive properties, are produced by human macrophages.
Hannelore Ehrenreich,Rob Anderson,Cecil H. Fox,Peter Rieckmann,Gary S. Hoffman,William D. Travis,John E. Coligan,John H. Kehrl,Anthony S. Fauci +8 more
TL;DR: The finding that human macrophage produce endothelins suggests an important role for these peptides in the microenvironment of tissue macrophages, which may have an essential function in blood vessel physiology, and aberrant production may contribute to vessel pathology.
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A disease-specific activity index for Wegener's granulomatosis: Modification of the Birmingham Vasculitis Activity Score
John H. Stone,Gary S. Hoffman,Peter A. Merkel,Yuan I. Min,Misty L. Uhlfelder,David B. Hellmann,Ulrich Specks,Nancy B. Allen,John C. Davis,Robert Spiera,Leonard H. Calabrese,Fredrick M. Wigley,Nicola Maiden,R. Valente,John L. Niles,Kenneth H. Fye,Joseph W. McCune,E. William St. Clair,Raashid Luqmani +18 more
TL;DR: The Birmingham Vasculitis Activity Score (BVAS) is a valid, disease-specific activity index for Wegener's granulomatosis (WG), which correlates well with the PGA, is sensitive to change, and has good inter- and intraobserver reliability.
Journal ArticleDOI
Surgical pathology of the lung in Wegener's granulomatosis. Review of 87 open lung biopsies from 67 patients.
TL;DR: The pulmonary pathologic features in 87 open lung biopsies from 67 patients with Wegener's granulo-matosis who were treated at a single institution from 1968 to 1990 are reported to illustrate the wide variation and broad spectrum of pathologic Features that can occur in pulmonary WG.