Gennaro Clemente

TL;DR: In this long-term, pragmatic trial, incidence of cardiovascular events was similar with sulfonylureas and pioglitazone as add-on treatments to metformin, although piog litazone was associated with fewer hypoglycaemia events.

TL;DR: Consumption of wholemeal wheat foods for 3 weeks reduces significantly fasting plasma cholesterol as well as LDL cholesterol levels in healthy individuals without major effects on glucose and insulin metabolism, antioxidant status and sub-clinical inflammation markers.

TL;DR: A 12-week whole-grain cereal-based diet, compared to refined cereals, reduced postprandial insulin and triglycerides responses, which may have implications for type 2 diabetes risk and cardiovascular disease.

TL;DR: A moderate intake of sc-FOS has no major effects on lipid metabolism, both in the fasting and in the postprandial period, in individuals with mild hypercholesterolaemia.

TL;DR: US H/R exhibits high sensitivity and specificity for detecting liver fatty changes and could therefore be a valuable analytic tool in clinical investigation, and indicates that quantitative evaluation of hepatic fat content can be performed using US H/r.