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Francesco Giorgino

Researcher at University of Bari

Publications -  326
Citations -  13867

Francesco Giorgino is an academic researcher from University of Bari. The author has contributed to research in topics: Diabetes mellitus & Type 2 diabetes. The author has an hindex of 56, co-authored 268 publications receiving 11174 citations. Previous affiliations of Francesco Giorgino include Joslin Diabetes Center & Harvard University.

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Journal ArticleDOI

Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial

Adrian F. Hernandez, +798 more
- 27 Oct 2018 - 
TL;DR: In patients with type 2 diabetes and cardiovascular disease, albiglutide was superior to placebo with respect to major adverse cardiovascular events, and evidence-based glucagon-like peptide 1 receptor agonists should be considered as part of a comprehensive strategy to reduce the risk of cardiovascular events.
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Oxidative stress and reactive oxygen species in endothelial dysfunction associated with cardiovascular and metabolic diseases

Maria Angela Incalza, +5 more
- 01 Jan 2018 - 
TL;DR: This review will focus on the main mechanisms involved in the onset of endothelial dysfunction, with particular focus on inflammation and aberrant ROS production and on their relationship with classical and non-classical cardiovascular risk factors, such as hypertension, metabolic disorders, and aging.
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Insulin receptor phosphorylation, insulin receptor substrate-1 phosphorylation, and phosphatidylinositol 3-kinase activity are decreased in intact skeletal muscle strips from obese subjects.

Laurie J. Goodyear, +5 more
- 01 May 1995 - 
TL;DR: It is concluded that impaired insulin-stimulated glucose uptake in skeletal muscle from severely obese subjects is accompanied by a deficiency in insulin receptor signaling, which may contribute to decreased insulin action.
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Feasibility and effectiveness of a disease and care management model in the primary health care system for patients with heart failure and diabetes (Project Leonardo).

Marco Matteo Ciccone, +10 more
- 28 Apr 2010 - 
TL;DR: Future studies should consider the possibility of incorporating a patient empowerment model which considers the patient as the most important member of the health team and care managers as key health care collaborators able to enhance and support services to patients provided by physicians in the primary health care system.
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The GH/IGF1 axis and signaling pathways in the muscle and bone: mechanisms underlying age-related skeletal muscle wasting and osteoporosis

Sebastio Perrini, +5 more
- 01 Jun 2010 - 
TL;DR: The molecular mechanisms of impaired GH and IGF1 signaling and action in aging, and their role in the pathogenesis of sarcopenia and osteoporosis are focused on.