G
George C. Tseng
Researcher at University of Pittsburgh
Publications - 254
Citations - 12062
George C. Tseng is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 52, co-authored 215 publications receiving 10124 citations. Previous affiliations of George C. Tseng include Lawrence Berkeley National Laboratory & Carnegie Mellon University.
Papers
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Issues in cDNA microarray analysis: quality filtering, channel normalization, models of variations and assessment of gene effects
TL;DR: A quality index, computed from duplicate spots on the same slide, is used to filter out outlying spots, poor quality genes and problematical slides and a rank invariant method is suggested to select non-differentially expressed genes and to construct normalization curves in comparative experiments.
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MicroRNA Expression Profiling of Thyroid Tumors: Biological Significance and Diagnostic Utility
TL;DR: It is demonstrated that various histopathological types of thyroid tumors have distinct miRNA profiles, which further differ within the same tumor type, reflecting specific oncogenic mutations.
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Comprehensive literature review and statistical considerations for GWAS meta-analysis
TL;DR: In this paper, a systematic search from PubMed and manual collection to obtain 620 genomic meta-analysis papers, of which 333 microarray metaanalysis papers are summarized as the basis of this paper and the other 249 GWAS meta analysis papers are discussed in the next companion paper.
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On ψ-Learning
TL;DR: A theory for ψ-learning is provided and it is shown that it essentially attains the optimal rates of convergence in two learning examples, and results from simulation studies and from breast cancer classification confirm the ability ofπ-learning to outperform SVM in generalization.
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Transcriptomic and genomic analysis of human hepatocellular carcinomas and hepatoblastomas
Jianhua Luo,Baoguo Ren,Sergei Keryanov,George C. Tseng,Uma N. M. Rao,Satdarshan P.S. Monga,Steven C. Strom,Anthony J. Demetris,Michael A. Nalesnik,Yan P. Yu,Sarangarajan Ranganathan,George K. Michalopoulos +11 more
TL;DR: It is found that HCC and adjacent non‐neoplastic cirrhotic tissue have considerable overlap in gene expression patterns compared to normal liver, and specific areas of the genome appear unstable in HCC.