L
Lars Rohlin
Researcher at University of California, Los Angeles
Publications - 23
Citations - 2457
Lars Rohlin is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Gene & Methanosarcina acetivorans. The author has an hindex of 15, co-authored 23 publications receiving 2297 citations.
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Issues in cDNA microarray analysis: quality filtering, channel normalization, models of variations and assessment of gene effects
TL;DR: A quality index, computed from duplicate spots on the same slide, is used to filter out outlying spots, poor quality genes and problematical slides and a rank invariant method is suggested to select non-differentially expressed genes and to construct normalization curves in comparative experiments.
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Physiology, Ecology, Phylogeny, and Genomics of Microorganisms Capable of Syntrophic Metabolism
Michael J. McInerney,Christopher G. Struchtemeyer,Jessica R. Sieber,Housna Mouttaki,Alfons J. M. Stams,Bernhard Schink,Lars Rohlin,Robert P. Gunsalus +7 more
TL;DR: The availability of the first complete genome sequences for four model microorganisms capable of syntrophic metabolism provides the genetic framework to begin dissecting the biochemistry of the marginal energy economies and interspecies interactions that are characteristic of the syntrophic lifestyle.
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Global Expression Profiling of Acetate-grown Escherichia coli∗
TL;DR: The gene expression profiles qualitatively agree with the metabolic flux changes and may serve as a predictor for gene function and metabolic flux distribution.
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The genome of Syntrophus aciditrophicus: Life at the thermodynamic limit of microbial growth
Michael J. McInerney,Lars Rohlin,Housna Mouttaki,Unmi Kim,Rebecca Krupp,Luis A. Rios-Hernandez,Jessica R. Sieber,Christopher G. Struchtemeyer,Anamitra Bhattacharyya,John W. Campbell,Robert P. Gunsalus +10 more
TL;DR: Genomic analysis confirms the S. aciditrophicus metabolic and regulatory commitment to a nonconventional mode of life compared with the prevailing understanding of microbiology.
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The genome of Syntrophomonas wolfei: new insights into syntrophic metabolism and biohydrogen production.
Jessica R. Sieber,David Sims,Cliff Han,Edwin Kim,Athanasios Lykidis,Alla Lapidus,Erin McDonnald,Lars Rohlin,David E. Culley,Robert P. Gunsalus,Michael J. McInerney +10 more
TL;DR: The genome sequence of S. wolfei reveals several core reactions that may be characteristic of syntrophic fatty acid metabolism and illustrates how biological systems produce hydrogen from thermodynamically difficult reactions.