G
George Du Toit
Researcher at Guy's and St Thomas' NHS Foundation Trust
Publications - 148
Citations - 7296
George Du Toit is an academic researcher from Guy's and St Thomas' NHS Foundation Trust. The author has contributed to research in topics: Peanut allergy & Food allergy. The author has an hindex of 35, co-authored 116 publications receiving 5604 citations. Previous affiliations of George Du Toit include European Academy of Allergy and Clinical Immunology & University of Cape Town.
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Journal ArticleDOI
Early consumption of peanuts in infancy is associated with a low prevalence of peanut allergy
George Du Toit,Yitzhak Katz,Peter Sasieni,David Mesher,Soheila J. Maleki,Helen R. Fisher,Adam T. Fox,Victor Turcanu,Tal Amir,Galia Zadik-Mnuhin,Adi Cohen,Irit Livne,Gideon Lack +12 more
TL;DR: It is demonstrated that Jewish children in the UK have a prevalence of PA that is 10-fold higher than that ofJewish children in Israel, and this difference is not accounted for by differences in atopy, social class, genetic background, or peanut allergenicity.
Journal ArticleDOI
AR101 Oral Immunotherapy for Peanut Allergy
Brian P. Vickery,Andrea Vereda,Thomas B. Casale,Kirsten Beyer,George Du Toit,Jonathan O'b Hourihane,Stacie M. Jones,Stacie M. Jones,Wayne G. Shreffler,Annette Marcantonio,Rezi Zawadzki,Lawrence Sher,W. Carr,Stanley Fineman,Leon Greos,Rima Rachid,M Dolores Ibáñez,Stephen A. Tilles,Amal Assa'ad,Caroline Nilsson,Ned Rupp,Michael J Welch,Gordon Sussman,Sharon Chinthrajah,Katharina Blumchen,Ellen Sher,Jonathan M. Spergel,Frederick E Leickly,Stefan Zielen,Julie Wang,Georgiana M Sanders,Robert A. Wood,Amarjit Cheema,Carsten Bindslev-Jensen,Stephanie A. Leonard,Rita Kachru,Douglas T Johnston,Frank C Hampel,Edwin H. Kim,Aikaterini Anagnostou,Jacqueline A. Pongracic,Moshe Ben-Shoshan,Hemant P Sharma,Allan Stillerman,Hugh H Windom,William H. Yang,Antonella Muraro,José Manuel Zubeldia,Vibha Sharma,Morna J. Dorsey,Hey Chong,Jason A. Ohayon,J. Andrew Bird,Tara F. Carr,Dareen Siri,Montserrat Fernandez-Rivas,David K Jeong,David Fleischer,Jay A. Lieberman,Anthony E.J. Dubois,Marina Tsoumani,Christina E. Ciaccio,Jay M. Portnoy,Lyndon E Mansfield,Stephen B Fritz,Bruce J. Lanser,Jonathan Matz,Hanneke N G Oude Elberink,Pooja Varshney,Stephen G Dilly,Daniel C. Adelman,A. Wesley Burks +71 more
TL;DR: Treatment with AR101 resulted in higher doses of peanut protein that could be ingested without dose‐limiting symptoms and in lower symptom severity during peanut exposure at the exit food challenge than placebo, in this phase 3 trial of oral immunotherapy in children and adolescents who were highly allergic to peanut.
Journal ArticleDOI
International consensus on allergy immunotherapy
Marek Jutel,Ioana Agache,Sergio Bonini,A. Wesley Burks,Moises A. Calderon,Walter Canonica,Linda Cox,Pascal Demoly,A. J. Frew,Robin O'Hehir,Jörg Kleine-Tebbe,Antonella Muraro,Gideon Lack,Désirée Larenas,Michael Levin,Harald Nelson,Ruby Pawankar,Oliver Pfaar,Ronald van Ree,Hugh A. Sampson,Alexandra F. Santos,George Du Toit,Thomas Werfel,Roy Gerth van Wijk,Luo Zhang,Cezmi A. Akdis +25 more
TL;DR: The international community of allergy specialists recognizes the need to develop a comprehensive consensus report to harmonize, disseminate, and implement the best AIT practice.
Journal ArticleDOI
Effect of Avoidance on Peanut Allergy after Early Peanut Consumption
George Du Toit,Peter H. Sayre,Graham Roberts,Michelle L. Sever,Kaitie Lawson,Henry T. Bahnson,Helen A. Brough,Alexandra F. Santos,Kristina M. Harris,Suzana Radulovic,Monica Basting,Victor Turcanu,Marshall Plaut,Gideon Lack +13 more
TL;DR: Among children at high risk for allergy in whom peanuts had been introduced in the first year of life and continued until 5 years of age, a 12-month period of peanut avoidance was not associated with an increase in the prevalence of peanut allergy.
Journal ArticleDOI
Household peanut consumption as a risk factor for the development of peanut allergy.
TL;DR: A dose-response relationship was observed between environmental (nonoral) peanut exposure and the development of PA, which was strongest for peanut butter, supporting the hypothesis that peanut sensitization occurs as a result of environmental exposure.