R
Rima Rachid
Researcher at Boston Children's Hospital
Publications - 61
Citations - 4091
Rima Rachid is an academic researcher from Boston Children's Hospital. The author has contributed to research in topics: Food allergy & Desensitization (medicine). The author has an hindex of 23, co-authored 58 publications receiving 3226 citations. Previous affiliations of Rima Rachid include Brigham and Women's Hospital & Harvard University.
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Journal ArticleDOI
TACI is mutant in common variable immunodeficiency and IgA deficiency.
Emanuela Castigli,Stephen A. Wilson,Lilit Garibyan,Rima Rachid,Francisco A. Bonilla,Lynda C. Schneider,Raif S. Geha +6 more
TL;DR: It is suggested that TACI mutations can result in CVID and IgAD, the same condition as common variable immunodeficiency and IgA deficiency.
Journal ArticleDOI
AR101 Oral Immunotherapy for Peanut Allergy
Brian P. Vickery,Andrea Vereda,Thomas B. Casale,Kirsten Beyer,George Du Toit,Jonathan O'b Hourihane,Stacie M. Jones,Stacie M. Jones,Wayne G. Shreffler,Annette Marcantonio,Rezi Zawadzki,Lawrence Sher,W. Carr,Stanley Fineman,Leon Greos,Rima Rachid,M Dolores Ibáñez,Stephen A. Tilles,Amal Assa'ad,Caroline Nilsson,Ned Rupp,Michael J Welch,Gordon Sussman,Sharon Chinthrajah,Katharina Blumchen,Ellen Sher,Jonathan M. Spergel,Frederick E Leickly,Stefan Zielen,Julie Wang,Georgiana M Sanders,Robert A. Wood,Amarjit Cheema,Carsten Bindslev-Jensen,Stephanie A. Leonard,Rita Kachru,Douglas T Johnston,Frank C Hampel,Edwin H. Kim,Aikaterini Anagnostou,Jacqueline A. Pongracic,Moshe Ben-Shoshan,Hemant P Sharma,Allan Stillerman,Hugh H Windom,William H. Yang,Antonella Muraro,José Manuel Zubeldia,Vibha Sharma,Morna J. Dorsey,Hey Chong,Jason A. Ohayon,J. Andrew Bird,Tara F. Carr,Dareen Siri,Montserrat Fernandez-Rivas,David K Jeong,David Fleischer,Jay A. Lieberman,Anthony E.J. Dubois,Marina Tsoumani,Christina E. Ciaccio,Jay M. Portnoy,Lyndon E Mansfield,Stephen B Fritz,Bruce J. Lanser,Jonathan Matz,Hanneke N G Oude Elberink,Pooja Varshney,Stephen G Dilly,Daniel C. Adelman,A. Wesley Burks +71 more
TL;DR: Treatment with AR101 resulted in higher doses of peanut protein that could be ingested without dose‐limiting symptoms and in lower symptom severity during peanut exposure at the exit food challenge than placebo, in this phase 3 trial of oral immunotherapy in children and adolescents who were highly allergic to peanut.
Journal ArticleDOI
Regulatory T cell reprogramming toward a Th2-cell-like lineage impairs oral tolerance and promotes food allergy.
Magali Noval Rivas,Magali Noval Rivas,Oliver T. Burton,Oliver T. Burton,Petra Wise,Louis-Marie Charbonnier,Louis-Marie Charbonnier,Peter Georgiev,Hans C. Oettgen,Hans C. Oettgen,Rima Rachid,Talal A. Chatila,Talal A. Chatila +12 more
TL;DR: It is shown that disease-susceptible mice with enhanced interleukin-4 receptor (IL-4R) signaling exhibited STAT6-dependent impaired generation and function of mucosal allergen-specific Treg cells, which might provide candidate therapeutic strategies in food allergy.
Journal ArticleDOI
A pilot study of omalizumab to facilitate rapid oral desensitization in high-risk peanut-allergic patients
Lynda C. Schneider,Rima Rachid,Jennifer S. LeBovidge,Emily A. Blood,Mudita Mittal,Dale T. Umetsu +5 more
TL;DR: Among children with high-risk peanut allergy, treatment with omalizumab may facilitate rapid oral desensitization and qualitatively improve the desensItization process.
Journal ArticleDOI
Mechanism of Recruitment of WASP to the Immunological Synapse and of Its Activation Following TCR Ligation
Yoji Sasahara,Rima Rachid,Michael Byrne,Miguel Angel de la Fuente,Robert T. Abraham,Narayanaswamy Ramesh,Raif S. Geha +6 more
TL;DR: The results suggest that the ZAP-70-CrkL-WIP pathway and PKCtheta link TCR to WASP activation, which is recruited to lipid rafts and the immunological synapse.