G
Gerald W. Feigenson
Researcher at Cornell University
Publications - 129
Citations - 15808
Gerald W. Feigenson is an academic researcher from Cornell University. The author has contributed to research in topics: Lipid bilayer & Vesicle. The author has an hindex of 52, co-authored 127 publications receiving 14211 citations. Previous affiliations of Gerald W. Feigenson include Keio University & California Institute of Technology.
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Membrane lipids: where they are and how they behave.
TL;DR: How do cells apply anabolic and catabolic enzymes, translocases and transporters, plus the intrinsic physical phase behaviour of lipids and their interactions with membrane proteins, to create the unique compositions and multiple functions of their individual membranes?
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Characterization of lipid bilayer phases by confocal microscopy and fluorescence correlation spectroscopy
TL;DR: Three-dimensional image reconstructions of confocal z-scans through giant unilamellar vesicles reveal the anisotropic morphology of coexisting phase domains on the surface of these vesicle with full two-dimensional resolution, answering a long-standing open question.
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A Microscopic Interaction Model of Maximum Solubility of Cholesterol in Lipid Bilayers
Juyang Huang,Gerald W. Feigenson +1 more
TL;DR: This treatment shows that dramatic structural and thermodynamic changes can occur at particular cholesterol mole fractions without any stoichiometric complex formation and the increase in acyl chain order parameter in cholesterol-phospholipid mixtures.
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Fluorescence probe partitioning between Lo/Ld phases in lipid membranes
TL;DR: Fluorescence markers effective for identification of coexisting macroscopic membrane phases in ternary lipid systems composed of phospholipids and cholesterol are found.
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Maximum solubility of cholesterol in phosphatidylcholine and phosphatidylethanolamine bilayers.
TL;DR: It is found that artifactual demixing of cholesterol can occur during conventional sample preparation and that this demixed cholesterol may produce artifactual cholesterol crystals, and phospholipid/cholesterol suspensions which are prepared by conventional methods may manifest variable, falsely low cholesterol solubility limits.