Showing papers by "Gerard A. Gioia published in 2015"
Alzheimer's Drug Discovery Foundation1, Safe Kids Worldwide2, Boston Medical Center3, University of Colorado Denver4, University of Virginia5, Icahn School of Medicine at Mount Sinai6, George Washington University7, University of California, Berkeley8, Stanford University9, Philippines National Collegiate Athletic Association10, Alzheimer's Association11, Burke Rehabilitation Hospital12, Harvard University13, Hastings Center14, University of Kentucky15, Novant Health16, Baylor College of Medicine17
TL;DR: This Expert Consensus Document is the result of a 1-day meeting convened by Safe Kids Worldwide, the Alzheimer's Drug Discovery Foundation, and the Andrews Institute for Orthopaedics and Sports Medicine to highlight knowledge gaps and areas of critically needed research.
Abstract: Sports-related concussions and repetitive subconcussive exposure are increasingly recognized as potential dangers to paediatric populations, but much remains unknown about the short-term and long- term consequences of these events, including potential cognitive impairment and risk of later-life dementia. This Expert Consensus Document is the result of a 1-day meeting convened by Safe Kids Worldwide, the Alzheimer's Drug Discovery Foundation, and the Andrews Institute for Orthopaedics and Sports Medicine. The goal is to highlight knowledge gaps and areas of critically needed research in the areas of concussion science, dementia, genetics, diagnostic and prognostic biomarkers, neuroimaging, sports injury surveillance, and information sharing. For each of these areas, we propose clear and achievable paths to improve the understanding, treatment and prevention of youth sports-related concussions.
64 citations
TL;DR: Student athletes and parents at Brain 101 schools significantly outperformed those at control schools on sports concussion knowledge, knowledge application, and behavioral intention to implement effective concussion management practices.
62 citations
TL;DR: A multimodal, developmentally adapted, standardized concussion assessment and active rehabilitation approach for children as young as 5 years old is described, with a specific focus on the school challenges faced by the recovering student.
Abstract: BACKGROUND: Significant attention has been focused on concussions in children, but a dearth of research evidence exists supporting clinical evaluation and management. AIM: The primary objective of this review paper is to describe a multimodal, developmentally adapted, standardized concussion assessment and active rehabilitation approach for children as young as 5 years old. METHODS: This study reviews the CDC-funded research programme, including the development of tools for post-concussion symptom assessment involving the child and parent, measurement of specific neurocognitive functions and assessment of dynamic cognitive exertional effects. RESULTS: A clinical approach to active, individualized, moderated concussion rehabilitation management is presented, including a 10-step guide to symptom management, with a specific focus on the school challenges faced by the recovering student. CONCLUSION: To better inform concussion practice across the developmental age spectrum, a significant need exists for further research evidence to refine clinical assessment methods and develop effective treatment approaches. Language: en
39 citations
TL;DR: Consistency of performance in an unmedicated ADHD group and a control group on concussion measures was consistent and the ADHD group performed better and comparable with controls when medicated.
36 citations
TL;DR: Sparing of extensive and severe EF deficits in SR-ALL survivors overall is suggested, however, a subset of survivors displays clinically significant executive dysfunction, suggesting a heightened susceptibility to disrupted metacognitive functions as survivors age.
Abstract: We aimed to evaluate parent-rated executive function (EF) in pediatric standard risk acute lymphoblastic leukemia (SR-ALL) survivors compared to a healthy comparison (HC) group. We hypothesized that SR-ALL survivors would have greater reported executive dysfunction compared to HC, and that those younger at the time of treatment would demonstrate greater EF difficulties. A sample of 256 SR-ALL survivors evaluated an average nine years after treatment were compared to HC matched for gender, assessment age, and maternal education. Profile analysis was used to compare the groups across EF scales on the BRIEF. The prevalence of clinical elevations in the groups was compared via chi square, and odds ratios were calculated. Regression models were applied to examine the role of age at diagnosis and age at assessment in reported EF. Results indicated that SR-ALL survivors' mean scores of EF are similar to HC, except for flexibility and initiation. Survivors were rated as having clinical impairments with flexibility, initiation, working memory, and emotional control at rates two to three times that of HC. The risk of working memory and self-monitoring deficits was greater in survivors who were older when assessed. There was no relationship between age at diagnosis or treatment regimen on EF. These findings suggest sparing of extensive and severe EF deficits in SR-ALL survivors overall. However, a subset of survivors displays clinically significant executive dysfunction. There appears to be a heightened susceptibility to disrupted metacognitive functions as survivors age. This has implications for how we monitor neurocognitive development and functioning of SR-ALL survivors, and highlights opportunities for cognitive interventions.
31 citations