Institution
Burke Rehabilitation Hospital
Healthcare•White Plains, New York, United States•
About: Burke Rehabilitation Hospital is a healthcare organization based out in White Plains, New York, United States. It is known for research contribution in the topics: Stroke & Rehabilitation. The organization has 108 authors who have published 143 publications receiving 10537 citations.
Papers published on a yearly basis
Papers
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Florey Institute of Neuroscience and Mental Health1, University of Calgary2, Boston Medical Center3, University of Zurich4, University of Missouri–Kansas City5, University of Oslo6, International Olympic Committee7, University of Toronto8, University of Michigan9, Vanderbilt University Medical Center10, University of Washington11, University of North Carolina at Chapel Hill12, University of British Columbia13, Cornell University14, Burke Rehabilitation Hospital15, University of Ottawa16, Medical College of Wisconsin17, University of New South Wales18, Monash University19, University of Melbourne20, McMaster University21, University of Medicine and Dentistry of New Jersey22, Princeton University23
TL;DR: The 4th International Conference on Concussion in Sport held in Zurich, November 2012 was attended by Paul McCrory, Willem H Meeuwisse, Mark Aubry, Jiří Dvořák, Ruben J Echemendia, Lars Engebretsen, Karen Johnston, Jeffrey S Kutcher, Martin Raftery, Allen Sills and Kathryn Schneider.
2,293 citations
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TL;DR: The findings suggest that the onset of dementia-related syndromes may be initiated by repetitive cerebral concussions in professionalFootball players, and an earlier onset of Alzheimer's disease in the retirees than in the general American male population.
Abstract: Objective Cerebral concussion is common in collision sports such as football, yet the chronic neurological effects of recurrent concussion are not well understood. The purpose of our study was to investigate the association between previous head injury and the likelihood of developing mild cognitive impairment (MCI) and Alzheimer's disease in a unique group of retired professional football players with previous head injury exposure. Methods A general health questionnaire was completed by 2552 retired professional football players with an average age of 53.8 (+/-13.4) years and an average professional football playing career of 6.6 (+/- 3.6) years. A second questionnaire focusing on memory and issues related to MCI was then completed by a subset of 758 retired professional football players (> or = 50 yr of age). Results on MCI were then cross-tabulated with results from the original health questionnaire for this subset of older retirees. Results Of the former players, 61% sustained at least one concussion during their professional football career, and 24% sustained three or more concussions. Statistical analysis of the data identified an association between recurrent concussion and clinically diagnosed MCI (chi = 7.82, df = 2, P = 0.02) and self-reported significant memory impairments (chi = 19.75, df = 2, P = 0.001). Retired players with three or more reported concussions had a fivefold prevalence of MCI diagnosis and a threefold prevalence of reported significant memory problems compared with retirees without a history of concussion. Although there was not an association between recurrent concussion and Alzheimer's disease, we observed an earlier onset of Alzheimer's disease in the retirees than in the general American male population. Conclusion Our findings suggest that the onset of dementia-related syndromes may be initiated by repetitive cerebral concussions in professional football players.
1,114 citations
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TL;DR: A proposed method to achieve this goal is a novel performance-based impedance control algorithm, which is triggered via speed, time, or EMG, which has already noted one very strong benefit, a significant reduction in arm tone.
Abstract: In this paper we describe the novel concept of performance-based progressive robot therapy that uses speed, time, or EMG thresholds to initiate robot assistance. We pioneered the clinical application of robot-assisted therapy focusing on stroke—the largest cause of disability in the US. We have completed several clinical studies involving well over 200 stroke patients. Research to date has shown that repetitive task-specific, goal-directed, robot-assisted therapy is effective in reducing motor impairments in the affected arm after stroke. One research goal is to determine the optimal therapy tailored to each stroke patient that will maximize his/her recovery. A proposed method to achieve this goal is a novel performance-based impedance control algorithm, which is triggered via speed, time, or EMG. While it is too early to determine the effectiveness of the algorithm, therapists have already noted one very strong benefit, a significant reduction in arm tone.
677 citations
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TL;DR: The results suggest that robotic manipulation of the impaired limb may favorably add to recovery following stroke and that robotics may provide new strategies for neurologic rehabilitation.
Abstract: Background: We used MIT-Manus, a robot designed to provide interactive, goal-directed motor activity for clinical neurologic applications. Objective: To test whether this robotic manipulation of the impaired limb influenced motor recovery in patients with hemiplegia. Methods: Sequential patients with a history of a single stroke and hemiplegia (N=20) hospitalized on the same acute care rehabilitation floor were enrolled in a standard rehabilitation program supplemented by either robot-aided therapy or sham robot-aided therapy. These 2 groups were comparable in age, initial physical impairment, and time between onset of the stroke and enrollment in the trial. Patients, clinical team members, and the clinical evaluator were blinded to the treatment group assignments. Standardized assessment tools measured outcomes. Results: Impairment and disability declined in both groups between hospital admission and discharge. The robot-treated group showed a greater degree of improvement in all 3 measures of motor recovery, and the change in motor status measured in the proximal upper limb musculature was significant (P=.002). No adverse events resulted from robot-assisted therapy. Conclusions: These results suggest that robotic manipulation of the impaired limb may favorably add to recovery following stroke and that robotics may provide new strategies for neurologic rehabilitation.
518 citations
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University of California, San Francisco1, John Hunter Hospital2, Alberta Children's Hospital3, University of North Carolina at Chapel Hill4, University of Chicago5, Boston Medical Center6, Western Michigan University7, Burke Rehabilitation Hospital8, Loyola University Medical Center9, University of Zurich10, University of Calgary11, Toronto Western Hospital12, Florey Institute of Neuroscience and Mental Health13, Spaulding Rehabilitation Hospital14
TL;DR: More research is needed to better understand the prevalence of chronic traumatic encephalopathy and other neurological conditions and diseases, and the extent to which they are related to concussions and/or repetitive neurotrauma sustained in sports.
Abstract: Objective Systematic review of possible long-term effects of sports-related concussion in retired athletes. Data sources Ten electronic databases. Study selection Original research; incidence, risk factors or causation related to long-term mental health or neurological problems; individuals who have suffered a concussion; retired athletes as the subjects and possible long-term sequelae defined as >10 years after the injury. Data extraction Study population, exposure/outcome measures, clinical data, neurological examination findings, cognitive assessment, neuroimaging findings and neuropathology results. Risk of bias and level of evidence were evaluated by two authors. Results Following review of 3819 studies, 47 met inclusion criteria. Some former athletes have depression and cognitive deficits later in life, and there is an association between these deficits and multiple prior concussions. Former athletes are not at increased risk for death by suicide (two studies). Former high school American football players do not appear to be at increased risk for later life neurodegenerative diseases (two studies). Some retired professional American football players may be at increased risk for diminishment in cognitive functioning or mild cognitive impairment (several studies), and neurodegenerative diseases (one study). Neuroimaging studies show modest evidence of macrostructural, microstructural, functional and neurochemical changes in some athletes. Conclusion Multiple concussions appear to be a risk factor for cognitive impairment and mental health problems in some individuals. More research is needed to better understand the prevalence of chronic traumatic encephalopathy and other neurological conditions and diseases, and the extent to which they are related to concussions and/or repetitive neurotrauma sustained in sports.
425 citations
Authors
Showing all 108 results
Name | H-index | Papers | Citations |
---|---|---|---|
Bruce T. Volpe | 78 | 256 | 22100 |
Rajiv R. Ratan | 70 | 200 | 14942 |
Gary E. Gibson | 68 | 261 | 16492 |
Jesse M. Cedarbaum | 44 | 155 | 11489 |
Thomas A. Ullman | 42 | 133 | 7500 |
Alexander W. Dromerick | 41 | 91 | 6030 |
Dylan J. Edwards | 34 | 100 | 4376 |
Michael Reding | 25 | 52 | 3434 |
Barry D. Jordan | 24 | 50 | 4773 |
Meheroz H. Rabadi | 16 | 51 | 1086 |
Mooyeon Oh-Park | 16 | 56 | 1057 |
Karuppagounder S. Saravanan | 13 | 14 | 785 |
Ambreena Siddiq | 13 | 13 | 1267 |
Michael Reding | 12 | 22 | 1009 |
Anne Felicia Ambrose | 12 | 29 | 3387 |