G
Gerard Folch
Researcher at Autonomous University of Barcelona
Publications - 5
Citations - 1629
Gerard Folch is an academic researcher from Autonomous University of Barcelona. The author has contributed to research in topics: Glioma & Population. The author has an hindex of 4, co-authored 5 publications receiving 1516 citations. Previous affiliations of Gerard Folch include Hebron University.
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Journal ArticleDOI
TGF-β Receptor Inhibitors Target the CD44high/Id1high Glioma-Initiating Cell Population in Human Glioblastoma
Judit Anido,Andrea Sáez-Borderías,Alba Gonzalez-Junca,Laura Rodon,Gerard Folch,Maria Ángeles Carmona,Rosa M. Prieto-Sánchez,Ignasi Barba,Elena Martínez-Sáez,Ludmila Prudkin,Isabel Cuartas,C. Raventós,Francisco Martínez-Ricarte,M. Antonia Poca,David Garcia-Dorado,Michael Lahn,Jonathan M. Yingling,Jordi Rodon,Juan Sahuquillo,Juan Sahuquillo,José Baselga,Joan Seoane,Joan Seoane +22 more
TL;DR: A cell population enriched for GICs that expresses high levels of CD44 and Id1 and tend to be located in a perivascular niche is identified, which confer poor prognosis in GBM patients.
Journal ArticleDOI
TGF-beta increases glioma-initiating cell self-renewal through the induction of LIF in human glioblastoma.
Silvia Peñuelas,Judit Anido,Rosa M. Prieto-Sánchez,Gerard Folch,Ignasi Barba,Isabel Cuartas,David Garcia-Dorado,M. Antonia Poca,Juan Sahuquillo,Juan Sahuquillo,José Baselga,José Baselga,Joan Seoane +12 more
TL;DR: The results show that TGF-beta and LIF have an essential role in the regulation of GICs in human glioblastoma.
Receptor Inhibitors Target the CD44(high)/Id1(high) Glioma-Initiating Cell Population in Human Glioblastoma
J Anido,A. Sáez-Borderías,Alba Gonzalez-Junca,L Rodón,Gerard Folch,MA Carmona,Rosa M. Prieto-Sánchez,I Barba,E. Martínez-Sáez,L Prudkin,I Cuartas,C Raventós,Francisco Martínez-Ricarte,MA Poca,D García-Dorado,MM Lahn,JM Yingling,J Rodón,J. Sahuquillo,J Baselga +19 more
Journal ArticleDOI
Myc inhibition is effective against glioma and reveals a role for Myc in proficient mitosis
Daniela Annibali,Daniela Annibali,Jonathan Whitfield,Emilia Favuzzi,Toni Jauset,Erika Serrano,Isabel Cuartas,Sara Redondo-Campos,Gerard Folch,Alba Gonzalez-Junca,Nicole M. Sodir,Nicole M. Sodir,Daniel Massó-Vallés,Marie-Eve Beaulieu,Lamorna Brown Swigart,Margaret M. Mc Gee,Maria Patrizia Somma,Sergio Nasi,Joan Seoane,Joan Seoane,Gerard I. Evan,Laura Soucek +21 more
TL;DR: Across all experimental models, Myc inhibition reduces proliferation, increases apoptosis and remarkably, elicits the formation of multinucleated cells that then arrest or die by mitotic catastrophe, revealing a new role for Myc in the proficient division of glioma cells.