G
Gerard van der Krogt
Researcher at Utrecht University
Publications - 4
Citations - 592
Gerard van der Krogt is an academic researcher from Utrecht University. The author has contributed to research in topics: Vinculin & Cadherin. The author has an hindex of 4, co-authored 4 publications receiving 515 citations. Previous affiliations of Gerard van der Krogt include University Medical Center Utrecht.
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Journal ArticleDOI
Vinculin associates with endothelial VE-cadherin junctions to control force-dependent remodeling
Stephan Huveneers,Joppe Oldenburg,Emma Spanjaard,Gerard van der Krogt,Ilya Grigoriev,Anna Akhmanova,Holger Rehmann,Johan de Rooij +7 more
TL;DR: A specialized subset of VE-cadherin adhesions senses cytoskeletal force and recruits Vinculin to control the stability of endothelial cell–cell junctions during their force-dependent remodeling.
Journal ArticleDOI
Vinculin-dependent Cadherin mechanosensing regulates efficient epithelial barrier formation
Floor Twiss,Quint le Duc,Suzanne van der Horst,Hamid Tabdili,Gerard van der Krogt,Ning Wang,Holger Rehmann,Stephan Huveneers,Stephan Huveneers,Deborah E. Leckband,Johan de Rooij +10 more
TL;DR: It is concluded that E-cadherin-based FAJs connect forming cell–cell adhesions to the contractile actomyosin cytoskeleton and are sites of Cadherin mechanosensing, which is a driving force in epithelial barrier formation.
Journal ArticleDOI
VASP, zyxin and TES are tension-dependent members of Focal Adherens Junctions independent of the α-catenin-vinculin module
Joppe Oldenburg,Gerard van der Krogt,Floor Twiss,Annika Bongaarts,Yasmin Habani,Johan A. Slotman,Adriaan B. Houtsmuller,Stephan Huveneers,Johan de Rooij +8 more
TL;DR: It is concluded that there are multiple force sensitive modules present at the FAJ that are activated at distinct locations along the cadherin-F-actin axis and regulate specific aspects of junction dynamics.
Journal ArticleDOI
Zygotic vinculin is not essential for embryonic development in zebrafish
TL;DR: It is concluded that vinculin is not of broad importance for the development and morphogenesis of zebrafish tissues.