G
Gergely Solecki
Researcher at German Cancer Research Center
Publications - 5
Citations - 264
Gergely Solecki is an academic researcher from German Cancer Research Center. The author has contributed to research in topics: Cancer & Antigen. The author has an hindex of 4, co-authored 5 publications receiving 166 citations. Previous affiliations of Gergely Solecki include University Hospital Heidelberg & Carl Zeiss AG.
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Journal ArticleDOI
Tumor microtubes convey resistance to surgical lesions and chemotherapy in gliomas
Sophie Weil,Matthias Osswald,Gergely Solecki,Julia Grosch,Erik Jung,Erik Jung,Dieter Lemke,Dieter Lemke,Miriam Ratliff,Miriam Ratliff,Daniel Hänggi,Wolfgang Wick,Frank Winkler,Frank Winkler +13 more
TL;DR: TMs can contribute to the resistance against standard treatment modalities in gliomas and specific inhibition of TMs is a promising approach to reduce local recurrence after surgery and lower resistance to chemotherapy.
Journal ArticleDOI
Proximity ligation assay evaluates IDH1R132H presentation in gliomas
Lukas Bunse,Lukas Bunse,Theresa Schumacher,Theresa Schumacher,Felix Sahm,Felix Sahm,Stefan Pusch,Stefan Pusch,Iris Oezen,Iris Oezen,Katharina J. Rauschenbach,Katharina J. Rauschenbach,Marina Gonzalez,Marina Gonzalez,Gergely Solecki,Gergely Solecki,Matthias Osswald,Matthias Osswald,David Capper,David Capper,Benedikt Wiestler,Benedikt Wiestler,Frank Winkler,Frank Winkler,Christel Herold-Mende,Andreas von Deimling,Wolfgang Wick,Michael Platten +27 more
TL;DR: The data suggest that PLA may be a useful tool to acquire information on whether an antigen is presented in situ, and this technique has potential to guide clinical studies that use antigen-specific cancer immunotherapy.
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Local blood coagulation drives cancer cell arrest and brain metastasis in a mouse model
Manuel Feinauer,Manuel Feinauer,Stefan W. Schneider,Anna S. Berghoff,Anna S. Berghoff,Anna S. Berghoff,Jose Ramon Robador,Cedric Tehranian,Cedric Tehranian,Matthia A. Karreman,Matthia A. Karreman,Varun Venkataramani,Varun Venkataramani,Varun Venkataramani,Gergely Solecki,Gergely Solecki,Gergely Solecki,Julia Grosch,Julia Grosch,Katharina Gunkel,Katharina Gunkel,Bogdana Kovalchuk,Bogdana Kovalchuk,Frank Thomas Mayer,Manuel Fischer,Michael O. Breckwoldt,Maik Brune,Yannik Schwab,Wolfgang Wick,Wolfgang Wick,Alexander Bauer,Frank Winkler,Frank Winkler +32 more
TL;DR: In vivo multiphoton laser-scanning microscopy of the entire brain metastatic cascade allowed unprecedented insights into how blood clot formation and von Willebrand factor deposition determine the arrest of circulating cancer cells and subsequent brain colonization in mice, discovering a novel and specific mechanism that is crucial for brain colonization.
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Glioblastoma multiforme restructures the topological connectivity of cerebrovascular networks.
Artur Hahn,Julia Bode,Thomas Krüwel,Gergely Solecki,Sabine Heiland,Martin Bendszus,Björn Tews,Frank Winkler,Michael O. Breckwoldt,Michael O. Breckwoldt,Felix T. Kurz +10 more
TL;DR: The results augment the understanding of cerebrovascular networks and offer a topological assessment of glioma-induced vascular remodeling, which may help understand the emergence of hypoxia and necrosis, and prove valuable for therapeutic interventions such as radiation or antiangiogenic therapy.
Journal ArticleDOI
Imaging Single Tumor Cells in Mice Using Multimodal Correlative Microscopy
Matthia A. Karreman,Luc Mercier,Nicole L. Schieber,Gergely Solecki,Guillaume Allio,Frank Winkler,Bernhard Ruthensteiner,Jacky G. Goetz,Yannick Schwab +8 more
TL;DR: This poster presents a poster presenting a probabilistic simulation of the response of the immune system to Tournaisian central giant cell reprograming.