Gergely Szalay

TL;DR: A precisely controlled model of brain injury induced by cerebral ischaemia combined with fast in vivo two-photon calcium imaging and selectivemicroglial manipulation shows that selective elimination of microglia leads to a striking, 60% increase in infarct size, which is reversed by microglial repopulation.

TL;DR: A high-resolution, acousto-optic two-photon microscope with continuous three-dimensional trajectory and random-access scanning modes that reaches near-cubic-millimeter scan range and can be adapted to imaging different spatial scales is developed.

TL;DR: This work proposes a method, MLspike, which returns the most likely spike train underlying the measured calcium fluorescence, which relies on a physiological model including baseline fluctuations and distinct nonlinearities for synthetic and genetically encoded indicators.

TL;DR: Single-cell–initiated, monosynaptically restricted retrograde transsynaptic tracing with rabies viruses expressing GCaMP6s is used to image, in vivo, the visual motion–evoked activity of individual layer 2/3 pyramidal neurons and their presynaptic networks across layers in mouse primary visual cortex.

TL;DR: A novel technology, 3D DRIFT AO scanning, which can extend each scanning point to small 3D lines, surfaces, or volume elements for flexible and fast imaging of complex structures simultaneously in multiple locations is presented.