G
Gershon Golomb
Researcher at Hebrew University of Jerusalem
Publications - 187
Citations - 7605
Gershon Golomb is an academic researcher from Hebrew University of Jerusalem. The author has contributed to research in topics: Restenosis & Controlled release. The author has an hindex of 45, co-authored 182 publications receiving 7217 citations. Previous affiliations of Gershon Golomb include National Institute of Standards and Technology & Boston Children's Hospital.
Papers
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Journal ArticleDOI
Sustained delivery and expression of DNA encapsulated in polymeric nanoparticles.
Hagit Cohen,Robert J. Levy,Jianchuan Gao,Ilia Fishbein,V Kousaev,S Sosnowski,S Slomkowski,Gershon Golomb +7 more
TL;DR: In vitro transfection by pDNA-NP resulted in significantly higher expression levels in comparison to naked pDNA, and plasmid DNA-NP treatment exhibited increased AP expression after 7 and 28 days indicating sustained activity of the NP.
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VEGFR-1-selective VEGF homologue PlGF is arteriogenic: evidence for a monocyte-mediated mechanism
Frederic Pipp,Matthias Heil,Katja Issbrücker,Tibor Ziegelhoeffer,Sandra Martin,Joop van den Heuvel,Herbert A. Weich,Borja Fernandez,Gershon Golomb,Peter Carmeliet,Wolfgang Schaper,Matthias Clauss +11 more
TL;DR: The ability of PlGF to enhance collateral growth in the rabbit model and to rescue impaired arteriogenesis in PlGF gene–deficient mice was abrogated, indicating that the arteriogenic activity observed with the VEGFR-1–specific PlGF is caused by its monocyte-activating properties.
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Lipophilic drug loaded nanospheres prepared by nanoprecipitation: effect of formulation variables on size, drug recovery and release kinetics
TL;DR: Nanoprecipitation protocol modifications were suggested to produce nanospheres combining ultrasmall size (<100 nm) with high drug recovery yield, and to reduce the surfactant amount in the formulation.
Journal Article
The role of glutaraldehyde-induced cross-links in calcification of bovine pericardium used in cardiac valve bioprostheses.
Gershon Golomb,Frederick J. Schoen,Mary Sue Smith,Judith A. Linden,Mark Dixon,Robert J. Levy +5 more
TL;DR: The amount of GLUT incorporated controls the extent of cross-links, which in turn directly determines tissue stability and calcification, in bovine pericardial tissue calcification.
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A new double emulsion solvent diffusion technique for encapsulating hydrophilic molecules in PLGA nanoparticles
TL;DR: The new NP preparation technique, double emulsion solvent diffusion (DES-D), resulted in improved formulation characteristics including smaller size, lower size distribution, higher encapsulation yield, and more biocompatible ingredients in comparison to classical methods.