M
Matthias Clauss
Researcher at Indiana University
Publications - 129
Citations - 11459
Matthias Clauss is an academic researcher from Indiana University. The author has contributed to research in topics: Endothelium & Endothelial stem cell. The author has an hindex of 44, co-authored 125 publications receiving 10952 citations. Previous affiliations of Matthias Clauss include Hoffmann-La Roche & Columbia University.
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The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kda tumor necrosis factor receptor
Matthias Grell,Eleni Douni,Harald Wajant,Matthias Löhden,Matthias Clauss,Beate Maxeiner,Spiros Georgopoulos,Werner Lesslauer,George Kollias,Klaus Pfizenmaier,Peter Scheurich +10 more
TL;DR: It is shown here that the transmembrane form of TNF is superior to soluble TNF in activating TNFR80 in activating TNF-induced cellular responses in various systems such as T cell activation, thymocyte proliferation, and granulocyte/macrophage colony-stimulating factor production.
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The vascular endothelial growth factor receptor Flt-1 mediates biological activities. Implications for a functional role of placenta growth factor in monocyte activation and chemotaxis.
Matthias Clauss,Herbert A. Weich,Georg Breier,Ulrike E. Knies,Wolfgang Röckl,Johannes Waltenberger,Werner Risau +6 more
TL;DR: Findings strongly suggest Flt-1 as a functional receptor for VEGF and PlGF in monocytes and endothelial cells and identify this receptor as a mediator of monocyte recruitment and procoagulant activity.
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Vascular permeability factor: a tumor-derived polypeptide that induces endothelial cell and monocyte procoagulant activity, and promotes monocyte migration.
Matthias Clauss,Marlene Gerlach,H Gerlach,J Brett,F. Wang,P C Familletti,Y. C.E. Pan,J. V. Olander,D. T. Connolly,David M. Stern +9 more
TL;DR: Results indicate that VPF can modulate the coagulant properties of endothelium and monocytes, and can promote monocyte migration into the tumor bed, which suggests one mechanism through which tumor-derived mediators can alter properties of the vessel wall.
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Isolation and characterization of two binding proteins for advanced glycosylation end products from bovine lung which are present on the endothelial cell surface.
Ann Marie Schmidt,M Vianna,Marlene Gerlach,J Brett,J Ryan,J Kao,Ciro Esposito,H Hegarty,Walter L. Hurley,Matthias Clauss +9 more
TL;DR: Results indicate that endothelial cells express specific cell surface molecules which mediate AGE-endothelial interaction, and represent a novel class of cell surface acceptor molecules for glucose-modified proteins which may promote degradation and/or transcytosis of the ligand, and modulation of cellular function.
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An angiogenic role for the human peptide antibiotic LL-37/hCAP-18
Rembert Koczulla,Georges von Degenfeld,Christian Kupatt,Florian Krötz,Stefan Zahler,Torsten Gloe,Katja Issbrücker,Pia Unterberger,Mohamed Zaiou,Mohamed Zaiou,Corinna Lebherz,Alexander Karl,Philip Raake,Achim Pfosser,Peter Boekstegers,Ulrich Welsch,Pieter S. Hiemstra,Claus Vogelmeier,Richard L. Gallo,Richard L. Gallo,Matthias Clauss,Robert Bals,Robert Bals +22 more
TL;DR: It is demonstrated that LL-37/hCAP-18 is a multifunctional antimicrobial peptide with a central role in innate immunity by linking host defense and inflammation with angiogenesis and arteriogenesis.