T
Timothy R. Orchard
Researcher at Imperial College Healthcare
Publications - 51
Citations - 4124
Timothy R. Orchard is an academic researcher from Imperial College Healthcare. The author has contributed to research in topics: Inflammatory bowel disease & Ulcerative colitis. The author has an hindex of 14, co-authored 47 publications receiving 3788 citations. Previous affiliations of Timothy R. Orchard include St Mary's Hospital & Imperial College London.
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Journal ArticleDOI
The second European evidence-based Consensus on the diagnosis and management of Crohn's disease: Definitions and diagnosis
Gert Van Assche,Axel Dignass,Julián Panés,Laurent Beaugerie,John A. Karagiannis,Mathieu Allez,Thomas Ochsenkühn,Timothy R. Orchard,Gerhard Rogler,Edouard Louis,Limas Kupčinskas,Gerassimos J. Mantzaris,Simon Travis,Eduard F. Stange +13 more
TL;DR: The aim of the Consensus is to promote a European perspective on the management of Crohn's disease and its dilemmas to avoid duplication of effort in the future.
Journal ArticleDOI
Guidelines for the management of inflammatory bowel disease in adults
Craig Mowat,Andrew Cole,Al Windsor,Tariq Ahmad,Ian D. Arnott,R Driscoll,Sally G. Mitton,Timothy R. Orchard,Matthew D. Rutter,Lisa Younge,Charlie W. Lees,Gwo-Tzer Ho,Jack Satsangi,Stuart Bloom +13 more
TL;DR: The present document is intended primarily for the use of clinicians in the United Kingdom, and serves to replace the previous BSG guidelines in IBD, while complementing recent consensus statements published by the European Crohn's and Colitis Organisation (ECCO).
Journal ArticleDOI
The effect of smoking after surgery for Crohn’s disease: a meta-analysis of observational studies
George E. Reese,Theodore G. Nanidis,Catherine A. Borysiewicz,Takayuki Yamamoto,Timothy R. Orchard,Paris P. Tekkis +5 more
TL;DR: Patients with Crohn’s disease who smoke have a 2.5-fold increased risk of surgical recurrence and a twofold risk of clinical recurrence compared to non-smokers and should be encouraged to stop smoking.
Journal ArticleDOI
HLA-DQA1*05 Carriage Associated With Development of Anti-Drug Antibodies to Infliximab and Adalimumab in Patients With Crohn's Disease
Aleksejs Sazonovs,Nicholas A Kennedy,Nicholas A Kennedy,Loukas Moutsianas,Graham A. Heap,Graham A. Heap,Daniel L. Rice,Mark Reppell,Claire Bewshea,Neil Chanchlani,Neil Chanchlani,Gareth J. Walker,Gareth J. Walker,Mandy H Perry,Timothy J. McDonald,Charlie W. Lees,J R Fraser Cummings,J R Fraser Cummings,Miles Parkes,John C. Mansfield,Peter M. Irving,Jeffrey C. Barrett,Dermot P.B. McGovern,James R Goodhand,James R Goodhand,Carl A. Anderson,Tariq Ahmad,Tariq Ahmad,Vinod B. Patel,Zia Mazhar,Rebecca Saich,Ben Colleypriest,Tony C.K. Tham,Tariq Iqbal,Vishal Kaushik,Senthil V. Murugesan,Salil Singh,Sean Weaver,Cathryn Preston,Assad Butt,Melissa A. Smith,Dharamveer Basude,Amanda Beale,Sarah Langlands,Natalie C. Direkze,Franco Torrente,Juan De La Revella Negro,Christopher Macdonald,Stephen M. Evans,Anton V J Gunasekera,Alka Thakur,David A Elphick,Achuth Shenoy,Chuka U. Nwokolo,Anjan Dhar,Andrew T. Cole,Anurag Agrawal,Stephen Bridger,Julie Doherty,Sheldon C. Cooper,Shanika de Silva,Craig Mowat,Phillip Mayhead,Charlie Lees,Gareth T. Jones,James W Hart,Daniel R. Gaya,Richard K. Russell,Lisa Gervais,Paul Dunckley,Tariq Mahmood,Paul R. Banim,Sunil Sonwalkar,Deb Ghosh,Rosemary H Phillips,Amer Azaz,Shaji Sebastian,Richard Shenderey,Lawrence Armstrong,Claire Bell,Radhakrishnan Hariraj,Helen Matthews,Hasnain Jafferbhoy,Christian P. Selinger,Veena Zamvar,John de Caestecker,Anne Willmott,Richard A. Miller,Palani Sathish Babu,Christos Tzivinikos,Stuart Bloom,Guy Chung-Faye,Nicholas M. Croft,John Fell,Marcus Harbord,Ailsa Hart,Ben Hope,James O. Lindsay,Joel Mawdsley,Alistair McNair,Kevin J. Monahan,Charles Murray,Timothy R. Orchard,Thankam Paul,Richard Pollok,Neil P. Shah,Sonia Bouri,Matthew W. Johnson,Anita Modi,Kasamu Dawa Kabiru,B K Baburajan,Bim Bhaduri,Andrew A. Fagbemi,Scott Levison,Jimmy K. Limdi,Gill Watts,Stephen Foley,Arvind Ramadas,George MacFaul,John C Mansfield,Leonie Grellier,Mary-Anne Morris,Mark Tremelling,Christopher J. Hawkey,Sian Kirkham,Charles Pj Charlton,Astor Rodrigues,Alison Simmons,Stephen Lewis,Jonathon Snook,Mark Tighe,Patrick Goggin,Aminda De Silva,Simon Lal,Mark S. Smith,Simon Panter,Fraser Cummings,Suranga Dharmisari,M J Carter,David Watts,Zahid Mahmood,Bruce McLain,Sandip Sen,Anna J Pigott,David Hobday,Emma Wesley,R B Johnston,Cathryn Edwards,John Beckly,Deven Vani,Subramaniam Ramakrishnan,Rakesh Chaudhary,Nigel Trudgill,Rachel Cooney,Andrew Bell,Neeraj Prasad,John N. Gordon,Matthew J Brookes,Andy Li,Stephen Gore +159 more
TL;DR: In an observational study, a genome-wide significant association between HLA-DQA1*05 and the development of antibodies against anti-TNF agents is found and a randomized controlled biomarker trial is required to determine whether pretreatment testing for HLA*05 improves patient outcomes by helping physicians select anti- TNF and combination therapies.
Journal ArticleDOI
Review article: defining remission in ulcerative colitis
Simon Travis,Peter D.R. Higgins,Timothy R. Orchard,C.J. van der Woude,Remo Panaccione,Alain Bitton,Colm O'Morain,Julián Panés,Andreas Sturm,Walter Reinisch,Michael A. Kamm,G. D’Haens +11 more
TL;DR: Aliment Pharmacol Ther 2011; 34: 113–124