Giampaolo Bianchi

TL;DR: It is concluded that NAFLD, in the presence of normoglycemia and normal or moderately increased body weight, is characterized by clinical and laboratory data similar to those found in diabetes and obesity.

TL;DR: Nonalcoholic fatty liver disease is associated with insulin resistance and hyperinsulinemia even in lean subjects with normal glucose tolerance, and genetic factors that reduce insulin sensitivity and increase serum triglyceride levels may be responsible for its development.

TL;DR: Patients who had steatohepatitis but were not alcoholics were treated with metformin (500 mg three times a day for 4 months), an agent that improves hepatic insulin sensitivity and insulin sensitivity, and liver volume decreased.

TL;DR: In advanced cirrhosis, long-term nutritional supplementation with oral BCAA is useful to prevent progressive hepatic failure and to improve surrogate markers and perceived health status.

TL;DR: Quality of life is variably impaired in cirrhosis, also in uncomplicated patients and non-life-threatening symptoms, such as muscle cramps, are of major concern.