G
Gian Kayser
Researcher at University of Freiburg
Publications - 170
Citations - 3883
Gian Kayser is an academic researcher from University of Freiburg. The author has contributed to research in topics: Lung cancer & Cancer. The author has an hindex of 29, co-authored 163 publications receiving 3283 citations. Previous affiliations of Gian Kayser include German Cancer Research Center & University Medical Center Freiburg.
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Journal ArticleDOI
The target landscape of clinical kinase drugs
Susan Klaeger,Susan Klaeger,Stephanie Heinzlmeir,Stephanie Heinzlmeir,Mathias Wilhelm,Harald Polzer,Harald Polzer,Binje Vick,Paul-Albert Koenig,Maria Reinecke,Maria Reinecke,Benjamin Ruprecht,Svenja Petzoldt,Svenja Petzoldt,Chen Meng,Jana Zecha,Jana Zecha,Katrin Reiter,Katrin Reiter,Huichao Qiao,Dominic Helm,Heiner Koch,Heiner Koch,Melanie Schoof,G. Canevari,Elena Casale,Stefania Re Depaolini,Annette Feuchtinger,Zhixiang Wu,Tobias Schmidt,Lars Rueckert,Wilhelm Becker,Jan Huenges,Anne-Kathrin Garz,Bjoern-Oliver Gohlke,Bjoern-Oliver Gohlke,Daniel P Zolg,Gian Kayser,Tõnu Vooder,Tõnu Vooder,Robert Preissner,Robert Preissner,Hannes Hahne,Neeme Tõnisson,Neeme Tõnisson,Karl Kramer,Katharina Götze,Florian Bassermann,Judith Schlegl,Hans-Christian Ehrlich,Stephan Aiche,Axel Walch,Philipp A. Greif,Philipp A. Greif,Sabine Schneider,Eduard R. Felder,Juergen Ruland,Guillaume Médard,Irmela Jeremias,Karsten Spiekermann,Karsten Spiekermann,Bernhard Kuster +61 more
TL;DR: A comprehensive analysis of 243 kinase inhibitors that are either approved for use or in clinical trials provides an open-access resource of target summaries that could help researchers develop better drugs, understand how existing drugs work, and design more effective clinical trials.
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Cancer cell invasion and EMT marker expression: a three-dimensional study of the human cancer-host interface.
Peter Bronsert,Kathrin Enderle-Ammour,Moritz Bader,Sylvia Timme,M Kuehs,Agnes Csanadi,Gian Kayser,Ilona Kohler,D Bausch,Jens Hoeppner,Ulrich T. Hopt,Tobias Keck,Elmar Stickeler,Bernward Passlick,Oliver Schilling,CP Reiss,Y Vashist,Thomas Brabletz,J. P. Berger,Johannes Lotz,Janine Olesch,Martin Werner,Ulrich F. Wellner +22 more
TL;DR: The relationship between current biological and clinical concepts such as cell migration modes, tumour budding and epithelial-mesenchymal transition (EMT) remains unclear in several aspects, especially for the'real' situation in human cancer as mentioned in this paper.
Journal ArticleDOI
A simple scoring system based on clinical factors related to pancreatic texture predicts postoperative pancreatic fistula preoperatively
Ulrich F. Wellner,Gian Kayser,Hryhoriy Lapshyn,Olivia Sick,Frank Makowiec,J Höppner,Ulrich T. Hopt,Tobias Keck +7 more
TL;DR: Preoperative stratification of patients regarding risk for POPF by simple clinical parameters is feasible and Pancreatic texture, as evaluated intraoperatively by the surgeon, is the strongest single predictive factor of POPF.
Journal ArticleDOI
Merkel cell polyomavirus sequences are frequently detected in nonmelanoma skin cancer of immunosuppressed patients
Ahmad Kassem,Kristin Technau,Anna Kordelia Kurz,Deepa Pantulu,Marie Löning,Gian Kayser,Elmar Stickeler,Wolfgang Weyers,Carlos Diaz,Martin Werner,Dorothee Nashan,Axel zur Hausen +11 more
TL;DR: The data show that MCPyV is a frequently reactivated virus in immunocompromized patients and contributes to the pathogenesis of NMSC, i.e., BD, SCC and BCC, in immunosuppressed patients and in addition, potentially to the Pathogenesis of a subset of sporadic BCC.
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Survival, disease-free interval, and associated tumor features in patients with colon/rectal carcinomas and their resected intra-pulmonary metastases
TL;DR: Pulmonary metastases occur even in patients with limited tumor-stages of primary colon/rectum cancer, and the major parameter to estimate the total survival of patients with lung metastases is the DFI, which correlated significantly with the tumor load and the number of metastases.