J
Jens Hoeppner
Researcher at University of Freiburg
Publications - 93
Citations - 2284
Jens Hoeppner is an academic researcher from University of Freiburg. The author has contributed to research in topics: Esophageal cancer & Medicine. The author has an hindex of 23, co-authored 85 publications receiving 1771 citations. Previous affiliations of Jens Hoeppner include University Medical Center Freiburg & Freiberg University of Mining and Technology.
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Journal ArticleDOI
Cancer cell invasion and EMT marker expression: a three-dimensional study of the human cancer-host interface.
Peter Bronsert,Kathrin Enderle-Ammour,Moritz Bader,Sylvia Timme,M Kuehs,Agnes Csanadi,Gian Kayser,Ilona Kohler,D Bausch,Jens Hoeppner,Ulrich T. Hopt,Tobias Keck,Elmar Stickeler,Bernward Passlick,Oliver Schilling,CP Reiss,Y Vashist,Thomas Brabletz,J. P. Berger,Johannes Lotz,Janine Olesch,Martin Werner,Ulrich F. Wellner +22 more
TL;DR: The relationship between current biological and clinical concepts such as cell migration modes, tumour budding and epithelial-mesenchymal transition (EMT) remains unclear in several aspects, especially for the'real' situation in human cancer as mentioned in this paper.
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ESOPEC: prospective randomized controlled multicenter phase III trial comparing perioperative chemotherapy (FLOT protocol) to neoadjuvant chemoradiation (CROSS protocol) in patients with adenocarcinoma of the esophagus (NCT02509286)
Jens Hoeppner,Florian Lordick,Thomas Brunner,Torben Glatz,Peter Bronsert,N Rothling,Claudia Schmoor,Dietmar Lorenz,Christian Ell,Ulrich T. Hopt,J. Rüdiger Siewert +10 more
TL;DR: The ESOPEC trial compares perioperative chemotherapy according to the FLOT protocol to neoadjuvant chemoradiation according toThe CROSS protocol in multimodal treatment of non-metastasized recectable adenocarcinoma of the esophagus and the gastroesophageal junction to identify the superior protocol with regard to patient survival, treatment morbidity and quality of life.
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Impact of different crystalloid volume regimes on intestinal anastomotic stability.
Goran Marjanovic,Christian Villain,Eva Juettner,Axel zur Hausen,Jens Hoeppner,Ulrich T. Hopt,Oliver Drognitz,Robert Obermaier +7 more
TL;DR: It is demonstrated for the first time in a systematic investigation, that the quantity of crystalloid infusion, applied intraoperatively, has a significant impact on functional (bursting pressure) and structural (hydroxyproline) stability of intestinal anastomoses in the early postoperative period.
Journal ArticleDOI
Postpancreatectomy hemorrhage--incidence, treatment, and risk factors in over 1,000 pancreatic resections.
Ulrich F. Wellner,B Kulemann,Hryhoriy Lapshyn,Jens Hoeppner,Olivia Sick,Frank Makowiec,Dirk Bausch,Ulrich T. Hopt,Tobias Keck +8 more
TL;DR: High-risk histopathology, age, transfusion, pancreatic fistula, postpancreatectomy hemorrhage and pancreatojejunostomy in pancreatoduodenectomies were independent predictors of mortality.
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Circulating tumor cells found in patients with localized and advanced pancreatic cancer.
B Kulemann,B Kulemann,Martha B. Pitman,Andrew S. Liss,Nakul P. Valsangkar,Carlos Fernandez-del Castillo,Keith D. Lillemoe,Jens Hoeppner,Mari Mino-Kenudson,Andrew L. Warshaw,Sarah P. Thayer +10 more
TL;DR: The ability of a simple new low-cost filtration device to capture, cytologically identify, and genetically analyze CTCs suggests a possible tool for the diagnosis and characterization of genetic alterations of PDAC.