G
Giancarlo Vanini
Researcher at University of Michigan
Publications - 50
Citations - 1077
Giancarlo Vanini is an academic researcher from University of Michigan. The author has contributed to research in topics: Wakefulness & Non-rapid eye movement sleep. The author has an hindex of 14, co-authored 46 publications receiving 771 citations. Previous affiliations of Giancarlo Vanini include University of the Republic.
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Journal ArticleDOI
Functional and Topological Conditions for Explosive Synchronization Develop in Human Brain Networks with the Onset of Anesthetic-Induced Unconsciousness.
Minkyung Kim,Minkyung Kim,George A. Mashour,Stefanie-Blain Moraes,Giancarlo Vanini,Vijay Tarnal,Ellen Janke,Anthony G. Hudetz,UnCheol Lee +8 more
TL;DR: This study demonstrates for the first time that the network conditions for ES, formerly shown in generic networks only, are present in empirically-derived functional brain networks and suggest a potential mechanism for rapid recovery from the lightly-anesthetized state.
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γ-Aminobutyric Acid–mediated Neurotransmission in the Pontine Reticular Formation Modulates Hypnosis, Immobility, and Breathing during Isoflurane Anesthesia
TL;DR: Decreasing pontine reticular formation GABA levels comprises one mechanism by which isoflurane causes loss of consciousness, altered cortical excitability, muscular hypotonia, and decreased respiratory rate.
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Neurophysiological correlates of sevoflurane-induced unconsciousness.
Stefanie Blain-Moraes,Vijay Tarnal,Giancarlo Vanini,Amir Alexander,Derek Rosen,Brenna P. Shortal,Ellen Janke,George A. Mashour +7 more
TL;DR: In humans, sevoflurane-induced unconsciousness is not correlated with anteriorization of alpha and related cross-frequency patterns, but rather by a disruption of phase–amplitude coupling in the parietal region and phase–phase relationships across the cortex.
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Relationship of critical dynamics, functional connectivity, and states of consciousness in large-scale human brain networks.
Heonsoo Lee,Daniel Golkowski,Denis Jordan,Denis Jordan,Sebastian Berger,Rüdiger Ilg,Rüdiger Ilg,Joseph Lee,George A. Mashour,UnCheol Lee,Michael S. Avidan,Stefanie Blain-Moraes,Goodarz Golmirzaie,Randall Hardie,Rosemary Hogg,Ellen Janke,Max B. Kelz,Kaitlyn Maier,Hannah R. Maybrier,Andrew R. McKinstry-Wu,Maxwell R. Muench,Andrew Ochroch,Ben J.A. Palanca,Paul Picton,E. Marlon Schwarz,Vijay Tarnal,Giancarlo Vanini,Phillip E. Vlisides +27 more
TL;DR: It is demonstrated that the partial phase locking at criticality shapes the functional connectivity and asymmetric anterior‐posterior PLE topography, with low (high) PLE for high (low) degree nodes, which differentiates various pharmacologic and pathologic states of consciousness.
Journal ArticleDOI
GABAergic processes in the mesencephalic tegmentum modulate the occurrence of active (rapid eye movement) sleep in guinea pigs
TL;DR: Data suggest that endogenous GABA acts on GABA(A) receptors within the vlPAG and dMRF to promote AS in the guinea pig.