G
Giarlã Cunha da Silva
Researcher at Universidade Federal de Viçosa
Publications - 10
Citations - 97
Giarlã Cunha da Silva is an academic researcher from Universidade Federal de Viçosa. The author has contributed to research in topics: Actinobacillus pleuropneumoniae & Biology. The author has an hindex of 3, co-authored 6 publications receiving 35 citations.
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Journal ArticleDOI
Galleria mellonella as an infection model: an in-depth look at why it works and practical considerations for successful application.
Monalessa Fábia Pereira,Ciro César Rossi,Giarlã Cunha da Silva,Jéssica Nogueira Rosa,Denise Mara Soares Bazzolli +4 more
TL;DR: The larva of the greater wax moth Galleria mellonella is an increasingly popular model for assessing the virulence of bacterial pathogens, and the effectiveness of antimicrobial agents, and an updated overview of the state of the art of research with G. mell onella- infection models is provided.
Journal ArticleDOI
p518, a small floR plasmid from a South American isolate of Actinobacillus pleuropneumoniae.
Giarlã Cunha da Silva,Ciro César Rossi,Mateus Ferreira Santana,Paul R. Langford,Janine T. Bossé,Denise Mara Soares Bazzolli +5 more
TL;DR: The smallest floR plasmid in the Pasteurellaceae has unique arrangement with complete strA, but partial strB and sul2 sequences, and is not transferrable by conjugation or natural transformation.
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Evidence of Illegitimate Recombination Between Two Pasteurellaceae Plasmids Resulting in a Novel Multi-Resistance Replicon, pM3362MDR, in Actinobacillus pleuropneumoniae
Yinghui Li,Yinghui Li,Giarlã Cunha da Silva,Yanwen Li,Ciro César Rossi,Roberto Fernandez Crespo,Susanna Williamson,Paul R. Langford,Denise Mara Soares Bazzolli,Janine T. Bossé +9 more
TL;DR: The newly identified multi-resistance plasmid, pM3362MDR, appears to have arisen through illegitimate recombination of pTetHS016 into the stop codon of the truncated strB gene in a pOV-like plasmids.
Journal ArticleDOI
Serovar-dependent differences in Hfq-regulated phenotypes in Actinobacillus pleuropneumoniae
Josicelli Souza Crispim,Thyara Ferreira da Silva,Newton Moreno Sanches,Giarlã Cunha da Silva,Monalessa Fábia Pereira,Ciro César Rossi,Yanwen Li,Vanessa S. Terra,Prerna Vohra,Brendan W. Wren,Paul R. Langford,Janine T. Bossé,Denise Mara Soares Bazzolli +12 more
TL;DR: It is supported that Hfq is a pleiotropic global regulator in A. pleuropneumoniae, but serovar-related differences exist, and the results highlight the importance of testing multiple strains/serovars within a given species when determining contributions of global regulators, such as HfQ, to expression of complex phenotypes.
Journal ArticleDOI
Comparative Genomics of Actinobacillus pleuropneumoniae Serotype 8 Reveals the Importance of Prophages in the Genetic Variability of the Species
Isabelle Gonçalves de Oliveira Prado,Giarlã Cunha da Silva,Josicelli Souza Crispim,Pedro Marcus Pereira Vidigal,Moysés Nascimento,Mateus Ferreira Santana,Denise Mara Soares Bazzolli +6 more
TL;DR: Mobile genetic elements, such as prophages, are important components of the differential portion of the A. pleuropneumoniae genome and demonstrate a central role in the evolution of the species.