G
Gideon Bollag
Researcher at Cetus Corporation
Publications - 8
Citations - 1998
Gideon Bollag is an academic researcher from Cetus Corporation. The author has contributed to research in topics: GTPase-activating protein & Gene product. The author has an hindex of 5, co-authored 8 publications receiving 1947 citations. Previous affiliations of Gideon Bollag include Chiron Corporation.
Papers
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Journal ArticleDOI
The GAP-related domain of the neurofibromatosis type 1 gene product interacts with ras p21
George A. Martin,David Viskoohil,Gideon Bollag,Peter C. McCabe,Walter J. Crosier,Heinz Haubruck,Leah Conroy,Robin D. Clark,Peter O'Connell,Richard M. Cawthon,Michael A. Innis,Frank McCormick +11 more
TL;DR: Kinetic measurements suggest that NF1 may be a significant regulator of ras p21 activity, particularly at low rAS p21 concentrations.
Journal ArticleDOI
Somatic mutations in the neurofibromatosis 1 gene in human tumors
Ying Li,Gideon Bollag,Robin Clark,Jeff Stevens,Leah Conroy,Daniel W. Fults,Kenneth Ward,Eitan Friedman,Wade S. Samowitz,Margaret Robertson,Paige Bradley,Frank McCormick,Ray White,Richard M. Cawthon +13 more
TL;DR: An amino acid substitution in the NF1 GRD, altering Lys-1423, is described that has occurred in three tumor types: colon adenocarcinoma, myelodysplastic syndrome, and anaplastic astrocytoma, and in one family with neurofibromatosis 1.
Journal ArticleDOI
Differential regulation of rasGAP and neurofibromatosis gene product activities.
Gideon Bollag,Frank McCormick +1 more
TL;DR: Results indicate that more than one GAP regulates p21 ras in the same cell, and that the mammalian cells contain both GAP activities and the oocytes have only p120-like GAP activity.