G
Gonzalo Sapisochin
Researcher at University Health Network
Publications - 211
Citations - 5063
Gonzalo Sapisochin is an academic researcher from University Health Network. The author has contributed to research in topics: Liver transplantation & Medicine. The author has an hindex of 24, co-authored 131 publications receiving 2787 citations. Previous affiliations of Gonzalo Sapisochin include Toronto General Hospital & University of Toronto.
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Journal ArticleDOI
Single cell RNA sequencing of human liver reveals distinct intrahepatic macrophage populations.
Sonya A. MacParland,Sonya A. MacParland,Jeff C. Liu,Xue Zhong Ma,Brendan T. Innes,Agata Bartczak,Blair K. Gage,Justin Manuel,Nicholas Khuu,Juan Echeverri,Ivan Linares,Rahul Gupta,Michael L Cheng,Lewis Y. Liu,Damra Camat,Sai W. Chung,Rebecca K. Seliga,Zigong Shao,Elizabeth Lee,Shinichiro Ogawa,Mina Ogawa,Michael D. Wilson,Jason E. Fish,Jason E. Fish,Markus Selzner,Anand Ghanekar,David R. Grant,Paul D. Greig,Gonzalo Sapisochin,Nazia Selzner,Neil Winegarden,Oyedele Adeyi,Oyedele Adeyi,Oyedele Adeyi,Gordon Keller,Gordon Keller,Gordon Keller,Gary D. Bader,Ian D. McGilvray +38 more
TL;DR: A map of the cellular landscape of the human liver using single-cell RNA sequencing is reported, and distinct populations of intrahepatic macrophages that may play specific roles in liver disease are identified.
Journal ArticleDOI
Liver transplantation for hepatocellular carcinoma: outcomes and novel surgical approaches
Gonzalo Sapisochin,Jordi Bruix +1 more
TL;DR: A comprehensive overview of the outcomes after liver transplantation for HCC, focusing on tumour recurrence in terms of surveillance, prevention and treatment is provided.
Journal ArticleDOI
The extended Toronto criteria for liver transplantation in patients with hepatocellular carcinoma: A prospective validation study
Gonzalo Sapisochin,Nicolas Goldaracena,Jerome M. Laurence,Martin J. Dib,Andrew S. Barbas,Anand Ghanekar,Sean P. Cleary,Les Lilly,Mark S. Cattral,Max Marquez,Markus Selzner,Eberhard L. Renner,Nazia Selzner,Ian D. McGilvray,Paul D. Greig,David R. Grant +15 more
TL;DR: Tumor differentiation and cancer‐related symptoms of HCC can be used to select patients with advanced HCC who are appropriate candidates for liver transplantation; alpha‐fetoprotein level limitations should be incorporated in the listing criteria for patients within or beyond the Milan criteria.
Journal ArticleDOI
Validation of a Risk Estimation of Tumor Recurrence After Transplant (RETREAT) Score for Hepatocellular Carcinoma Recurrence After Liver Transplant.
Neil Mehta,Julie K. Heimbach,Denise M. Harnois,Gonzalo Sapisochin,Jennifer L. Dodge,David D. Lee,Justin M. Burns,William Sanchez,Paul D. Greig,David R. Grant,John P. Roberts,Francis Y. Yao +11 more
TL;DR: A simple and novel prognostic score that may improve post-LT HCC surveillance strategies and help identify patients who may benefit from future adjuvant therapies is developed and validated.
Journal ArticleDOI
Liver transplantation for "very early" intrahepatic cholangiocarcinoma: International retrospective study supporting a prospective assessment.
Gonzalo Sapisochin,Marcelo Facciuto,Laura Rubbia-Brandt,J. Marti,Neil Mehta,Francis Y. Yao,Eric Vibert,Daniel Cherqui,David R. Grant,Roberto Hernandez-Alejandro,C.H. Dale,Alessandro Cucchetti,A.D. Pinna,Shin Hwang,Sung-Gyu Lee,Vatche G. Agopian,Ronald W. Busuttil,Sumera Rizvi,Julie K. Heimbach,M. Montenovo,Jorge Reyes,Manuela Cesaretti,Olivier Soubrane,Trevor Reichman,John Seal,Peter T. W. Kim,G Klintmalm,Carlo Sposito,Vincenzo Mazzaferro,Philipp Dutkowski,Pierre-Alain Clavien,Christian Toso,Pietro Majno,Norman M. Kneteman,C. Saunders,Jordi Bruix +35 more
TL;DR: Patients with cirrhosis and very early iCCA may become candidates for liver transplantation; a prospective multicenter clinical trial is needed to further confirm these results.