Gordana Rubeša

TL;DR: Functional tests clearly showed the deficiency in early spontaneous cytotoxic potential of PBL from elderly persons due to relative P deficiency, which can be corrected by stimulation of cytolytic cells with target cells and interleukin-2 (IL-2).

TL;DR: The aim was to investigate the distribution and the phenotype of P+ cells in decidua of pregnancy and to find out if the number of perforin‐positive cells in pregnancy is larger than in any other pathological condition.

TL;DR: The aim was to detect expression of perforin in both decidual lymphocytes and peripheral blood lymphocytes in the first trimester of pathological pregnancies: Anembryonic pregnancy and missed abortion.

TL;DR: The interaction of viable trophoblast with intrauterine decidua appears to be a prerequisite for the activation of NAD suppressor cells, and both NAD and adherent (AD) decidual leukocytes from NP and AP produced very strong suppression of PHA or alloantigen-induced PBL proliferation.

TL;DR: The hypothesis that cytotoxicity mediated by perforin may be an important effector mechanism in the rejection of allografted kidneys is confirmed and can be used to discriminate between immunosuppressed patients who are immunologically quiescent and those who undergo transplant rejection.