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Natasa Strbo
Researcher at University of Miami
Publications - 83
Citations - 2136
Natasa Strbo is an academic researcher from University of Miami. The author has contributed to research in topics: Immune system & Perforin. The author has an hindex of 26, co-authored 74 publications receiving 1783 citations. Previous affiliations of Natasa Strbo include University of Rijeka.
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Journal ArticleDOI
Innate and Adaptive Immune Responses in Wound Epithelialization
TL;DR: A better understanding of the epithelial cells (keratinocytes), immune cells, and mechanisms that contribute to an effective wound healing process is necessary so that new strategies for successful wounds treatment can be devised.
Journal ArticleDOI
Age-Related Decline of Perforin Expression in Human Cytotoxic T Lymphocytes and Natural Killer Cells
Daniel Rukavina,Gordana Laškarin,Gordana Rubeša,Natasa Strbo,Ivica Bedenicki,Darko Manestar,Mario Glavas,Stephen E. Christmas,Eckhard R. Podack +8 more
TL;DR: Functional tests clearly showed the deficiency in early spontaneous cytotoxic potential of PBL from elderly persons due to relative P deficiency, which can be corrected by stimulation of cytolytic cells with target cells and interleukin-2 (IL-2).
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Identification of a subpopulation of macrophages in mammary tumor-bearing mice that are neither M1 nor M2 and are less differentiated.
Marta Torroella-Kouri,Risset Silvera,Dayron Rodriguez,Raul Caso,Alwi M. Shatry,Shannon J. Opiela,Dan Ilkovitch,Reto A. Schwendener,Vijaya Iragavarapu-Charyulu,Yoslayma Cardentey,Natasa Strbo,Diana M. Lopez +11 more
TL;DR: The results suggest that T-PEMs are less differentiated and represent a newly derived population from blood monocytes, and show that transforming growth factor-beta and prostaglandin E(2), two immunosuppressive tumor-derived factors, may be involved in this phenomenon.
Journal ArticleDOI
Differential effects of IL-21 and IL-15 on perforin expression, lysosomal degranulation, and proliferation in CD8 T cells of patients with human immunodeficiency virus-1 (HIV).
Lesley J. White,Subramaniam Krishnan,Natasa Strbo,Huanliang Liu,Michael A. Kolber,Mathias G. Lichtenheld,Rajendra Pahwa,Savita Pahwa +7 more
TL;DR: CD8 T cells of patients with HIV can be modulated by IL-21 to increase perforin expression without undergoing overt cellular activation, and could potentially be useful for its per forin-enhancing properties in anti-HIV immunotherapy.
Journal ArticleDOI
Deregulated immune cell recruitment orchestrated by FOXM1 impairs human diabetic wound healing.
Andrew P. Sawaya,Rivka C. Stone,Stephen R. Brooks,Irena Pastar,Ivan Jozic,Kowser Hasneen,Katelyn O’Neill,S. Mehdizadeh,Cheyanne R. Head,Natasa Strbo,Maria I. Morasso,Marjana Tomic-Canic +11 more
TL;DR: The role of a perturbed, ineffective inflammatory response is underscored as a major contributor to the pathogenesis of DFUs, which is facilitated by FOXM1-mediated deregulation of recruitment of neutrophils and macrophages, revealing a potential therapeutic strategy.