Daniel Rukavina

TL;DR: It is shown that under certain conditions the CD8+ T-lymphocyte subset can be dispensable for clearance of cytomegalovirus, and eliminated infectious virus with a clearance kinetics similar to that of normal mice.

TL;DR: The promiscuous decoy receptor for inflammatory CC chemokines D6 plays a nonredundant role in the protection against fetal loss caused by systemic inflammation and antiphospholipid antibodies.

TL;DR: Uterine dendritic cells within the decidua serve as antigen-presenting cells with the unique ability to induce primary immune responses and may also act to induce immunologic tolerance and regulation of T cell-mediated immunity.

TL;DR: Human decidual NK cell potential functions at the maternal-fetal interface are not yet clearly established but several hypotheses are being evaluated, including control of extravillous invasion, control of uterine vascular remodeling, and local anti-viral activity.

TL;DR: D6–/– mice showed an anticipated and exacerbated inflammatory response in a model of skin inflammation and the absence of D6 resulted in increase cellularity and inflammatory‐chemokine levels in draining lymph nodes, suggesting that D6 is a decoy receptor structurally adapted and strategically located to tune tissue inflammation and control transfer of inflammatory chemokines to draining lymph node.