G
Grace Brannigan
Researcher at Rutgers University
Publications - 62
Citations - 1948
Grace Brannigan is an academic researcher from Rutgers University. The author has contributed to research in topics: Ligand-gated ion channel & Chemistry. The author has an hindex of 22, co-authored 50 publications receiving 1725 citations. Previous affiliations of Grace Brannigan include Temple University & University of Pennsylvania.
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Embedded cholesterol in the nicotinic acetylcholine receptor
TL;DR: It is shown that the nAChR contains internal sites capable of containing cholesterol, whose occupation stabilizes the protein structure, and bound cholesterol directly supports contacts between the agonist-binding domain and the pore that are thought to be essential for activation of the receptor.
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Implicit solvent simulation models for biomembranes.
TL;DR: Various coarse-grained simulation methodologies are reviewed with special emphasis on methods and models that do not require the explicit simulation of water, demonstrating their potential for simulating a variety of biologically relevant phenomena at the membrane surface.
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A Consistent Model for Thermal Fluctuations and Protein-Induced Deformations in Lipid Bilayers
TL;DR: An elastic Hamiltonian for membrane energetics is presented that captures bilayer undulation and peristaltic deformations over all wavelengths, including the short wavelength protrusion regime, and predicts previously overlooked relationships between these curves.
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Membrane Protein Structure, Function, and Dynamics: a Perspective from Experiments and Theory
Zoe Cournia,Toby W. Allen,Toby W. Allen,Ioan Andricioaei,Bruno Antonny,Daniel Baum,Grace Brannigan,Nicolae-Viorel Buchete,Jason Deckman,Lucie Delemotte,Coral del Val,Ran Friedman,Paraskevi Gkeka,Hans-Christian Hege,Jérôme Hénin,Marina A. Kasimova,Marina A. Kasimova,Antonios Kolocouris,Michael L. Klein,Syma Khalid,M. Joanne Lemieux,Norbert Lindow,Mahua Roy,Jana Selent,Mounir Tarek,Mounir Tarek,Florentina Tofoleanu,Stefano Vanni,Sinisa Urban,David J. Wales,Jeremy C. Smith,Ana-Nicoleta Bondar +31 more
TL;DR: Current studies in computational and experimental membrane protein biophysics are presented, and how they address outstanding challenges in understanding the complex environmental effects on the structure, function, and dynamics of membrane proteins are shown.
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Solvent-free simulations of fluid membrane bilayers.
TL;DR: In this article, a molecular level model for lipid bilayers is presented, where a simple three parameter potential between pairs of lipids gives rise to a rich assortment of phases including micelles, fluid bilayers, and gel-like bilayers.