J
Jana Selent
Researcher at Pompeu Fabra University
Publications - 84
Citations - 2148
Jana Selent is an academic researcher from Pompeu Fabra University. The author has contributed to research in topics: G protein-coupled receptor & Receptor. The author has an hindex of 23, co-authored 71 publications receiving 1581 citations. Previous affiliations of Jana Selent include University of Santiago de Compostela & Humboldt University of Berlin.
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Journal ArticleDOI
MEMBPLUGIN: studying membrane complexity in VMD.
Ramon Guixà-González,Ismael Rodríguez-Espigares,Juan Manuel Ramírez-Anguita,Pau Carrió-Gaspar,Hector Martinez-Seara,Toni Giorgino,Jana Selent +6 more
TL;DR: MEMBPLUGIN is a plugin for the Visual Molecular Dynamics package that provides algorithms to measure a host of essential biophysical properties in simulated membranes and is accessible both through a user-friendly graphical interface and as command-line procedures to be invoked in analysis scripts.
Journal ArticleDOI
Membrane Protein Structure, Function, and Dynamics: a Perspective from Experiments and Theory
Zoe Cournia,Toby W. Allen,Toby W. Allen,Ioan Andricioaei,Bruno Antonny,Daniel Baum,Grace Brannigan,Nicolae-Viorel Buchete,Jason Deckman,Lucie Delemotte,Coral del Val,Ran Friedman,Paraskevi Gkeka,Hans-Christian Hege,Jérôme Hénin,Marina A. Kasimova,Marina A. Kasimova,Antonios Kolocouris,Michael L. Klein,Syma Khalid,M. Joanne Lemieux,Norbert Lindow,Mahua Roy,Jana Selent,Mounir Tarek,Mounir Tarek,Florentina Tofoleanu,Stefano Vanni,Sinisa Urban,David J. Wales,Jeremy C. Smith,Ana-Nicoleta Bondar +31 more
TL;DR: Current studies in computational and experimental membrane protein biophysics are presented, and how they address outstanding challenges in understanding the complex environmental effects on the structure, function, and dynamics of membrane proteins are shown.
Journal ArticleDOI
Membrane cholesterol access into a G-protein-coupled receptor.
Ramon Guixà-González,José Luis Albasanz,Ismael Rodríguez-Espigares,Manuel Pastor,Ferran Sanz,Maria Marti-Solano,Moutusi Manna,Hector Martinez-Seara,Hector Martinez-Seara,Peter W. Hildebrand,Mairena Martín,Jana Selent +11 more
TL;DR: Overall, it is shown that cholesterol's impact on A2AR-binding affinity goes beyond pure allosteric modulation and unveils a new interaction mode between cholesterol and the A2 AR that could potentially apply to other GPCRs.
Journal ArticleDOI
Induced effects of sodium ions on dopaminergic G-protein coupled receptors.
TL;DR: Detailed quantitative information is provided about binding of sodium ions in the D2 receptor and a possibly important sodium-induced conformational change for modulation of D2 receptors function is reported.
Journal ArticleDOI
Membrane omega-3 fatty acids modulate the oligomerisation kinetics of adenosine A2A and dopamine D2 receptors
Ramon Guixà-González,Matti Javanainen,Maricel Gómez-Soler,Begoña Cordobilla,Joan Carles Domingo,Ferran Sanz,Manuel Pastor,Francisco Ciruela,Francisco Ciruela,Hector Martinez-Seara,Jana Selent +10 more
TL;DR: It is revealed for the first time that membrane ω-3 PUFAs play a key role in GPCR oligomerisation kinetics, which may have important implications for neuropsychiatric conditions like schizophrenia or Parkinson’s disease.