G
Guang Hu
Researcher at Chongqing University of Technology
Publications - 15
Citations - 550
Guang Hu is an academic researcher from Chongqing University of Technology. The author has contributed to research in topics: Vascular endothelial growth factor & Angiogenesis. The author has an hindex of 10, co-authored 14 publications receiving 487 citations. Previous affiliations of Guang Hu include University of Macau.
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Journal ArticleDOI
Calycosin promotes angiogenesis involving estrogen receptor and mitogen-activated protein kinase (MAPK) signaling pathway in zebrafish and HUVEC.
Jing Yan Tang,Shang Li,Zhen Hua Li,Zai Jun Zhang,Guang Hu,Lorita Chi Veng Cheang,Deepa Alex,Maggie Pui Man Hoi,Yiu Wa Kwan,Shun Wan Chan,George P.H. Leung,Simon Ming-Yuen Lee +11 more
TL;DR: It is revealed, for the first time, that calycosin acts as a selective estrogen receptor modulator (SERM) to promote angiogenesis, at least in part through VEGF-VEGFR2 and MAPK signaling pathways.
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Angiogenic Effect of Saponin Extract from Panax notoginseng on HUVECs In Vitro and Zebrafish In Vivo
Si-Jia Hong,Jian-Bo Wan,Yi Zhang,Guang Hu,Hui-Chao Lin,Sai Wang Seto,Yiu Wa Kwan,Zhi-Xiu Lin,Yitao Wang,Simon Ming-Yuen Lee +9 more
TL;DR: The results suggest that PNS can promote angiogenesis, and that the proangiogenic effects involve the VEGF‐KDR/Flk‐1 and PI3K‐Akt‐eNOS signaling pathways.
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Furanodiene induces G2/M cell cycle arrest and apoptosis through MAPK signaling and mitochondria-caspase pathway in human hepatocellular carcinoma cells.
Yu Xiao,Feng-Qing Yang,Shao-Ping Li,Jian-Li Gao,Guang Hu,Sin-Cheng Lao,Emilia Leong Conceição,Kwok-Pui Fung,Yi-Tao Wangl,Simon Ming-Yuen Lee +9 more
TL;DR: It is found that furanodiene induced mitochondrial transmembrane depolarization, release of mitochondrial cytochrome c, activation of caspases-3 and the cleavage of PARP, which involved activation of p38 and inhibition of ERK mitogen-activated protein kinase (MAPK) signaling.
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Essential oil of Curcuma wenyujin induces apoptosis in human hepatoma cells.
TL;DR: CWO exhibits an antiproliferative effect in HepG2 cells by inducing apoptosis, and results suggest a potential of CWO as a chemotherapeutic agent.
Journal ArticleDOI
Pro-angiogenic activity of astragaloside IV in HUVECs in vitro and zebrafish in vivo.
Yi Zhang,Guang Hu,Shang Li,Zhen Hua Li,Che Oi Lam,Si Jia Hong,Yiu Wa Kwan,Shun Wan Chan,George P.H. Leung,Simon Ming-Yuen Lee +9 more
TL;DR: The results suggest that AS-IV exerts potential pro-angiogenic effects in vitro and in vivo, and that its pro-ANGiogenic activity probably involves both VEGF- and Akt-dependent signaling pathways.