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Yiu Wa Kwan
Researcher at The Chinese University of Hong Kong
Publications - 132
Citations - 3544
Yiu Wa Kwan is an academic researcher from The Chinese University of Hong Kong. The author has contributed to research in topics: Endothelium & Angiogenesis. The author has an hindex of 32, co-authored 126 publications receiving 3093 citations. Previous affiliations of Yiu Wa Kwan include University of Rochester & University of Strathclyde.
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Journal ArticleDOI
A review of the pharmacological effects of Arctium lappa (burdock).
Yuk Shing Chan,Long Ni Cheng,Jian Hong Wu,Enoch Chan,Yiu Wa Kwan,Simon Ming-Yuen Lee,George P.H. Leung,Peter H. Yu,Shun Wan Chan +8 more
TL;DR: In the root, the active ingredients have been found to “detoxify” blood in terms of TCM and promote blood circulation to the skin surface, improving the skin quality/ texture and curing skin diseases like eczema.
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Subunit-dependent modulation of recombinant L-type calcium channels. Molecular basis for dihydropyridine tissue selectivity.
TL;DR: This study measures the DHP modulation of recombinant calcium channel activity in cells transfected with alpha 1 subunits of cardiac and smooth muscle L-type calcium channels and finds subunit-dependent differences in the voltage and concentration dependence of channel modulation.
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Calycosin promotes angiogenesis involving estrogen receptor and mitogen-activated protein kinase (MAPK) signaling pathway in zebrafish and HUVEC.
Jing Yan Tang,Shang Li,Zhen Hua Li,Zai Jun Zhang,Guang Hu,Lorita Chi Veng Cheang,Deepa Alex,Maggie Pui Man Hoi,Yiu Wa Kwan,Shun Wan Chan,George P.H. Leung,Simon Ming-Yuen Lee +11 more
TL;DR: It is revealed, for the first time, that calycosin acts as a selective estrogen receptor modulator (SERM) to promote angiogenesis, at least in part through VEGF-VEGFR2 and MAPK signaling pathways.
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Simultaneous quantification of five major biologically active ingredients of saffron by high-performance liquid chromatography.
TL;DR: Results indicate that the developed HPLC assay can be readily utilized as a quality control method for crocin-containing medicinal herbs.
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The angiogenic effects of Angelica sinensis extract on HUVEC in vitro and zebrafish in vivo
Hio Wa Lam,Hui Chao Lin,Hui Chao Lin,Sin Cheng Lao,Jian-Li Gao,Si Jia Hong,Chi Weng Leong,Patrick Y K Yue,Yiu Wa Kwan,Anskar Y.H. Leung,Yitao Wang,Simon Ming-Yuen Lee,Simon Ming-Yuen Lee +12 more
TL;DR: Results suggest that Angelica sinensis extract can promote angiogenesis, and that the angiogenic effects involve p38 and JNK 1/2 phosphorylation.