G
Guido van den Thillart
Researcher at Leiden University
Publications - 98
Citations - 4382
Guido van den Thillart is an academic researcher from Leiden University. The author has contributed to research in topics: Carp & Common carp. The author has an hindex of 35, co-authored 98 publications receiving 4085 citations.
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Journal ArticleDOI
The king cobra genome reveals dynamic gene evolution and adaptation in the snake venom system
Freek J. Vonk,Freek J. Vonk,Freek J. Vonk,Nicholas R. Casewell,Nicholas R. Casewell,Christiaan V. Henkel,Alysha Heimberg,Hans J. Jansen,Ryan J.R. McCleary,Harald M. E. Kerkkamp,Rutger A. Vos,Isabel Guerreiro,Juan J. Calvete,Wolfgang Wüster,Anthony E. Woods,Jessica M. Logan,Robert A. Harrison,Todd A. Castoe,Todd A. Castoe,A. P. Jason de Koning,A. P. Jason de Koning,David D. Pollock,Mark Yandell,Diego Calderon,Camila Renjifo,Rachel B. Currier,David Salgado,David Salgado,Davinia Pla,Libia Sanz,Asad S. Hyder,José M. C. Ribeiro,Jan W. Arntzen,Guido van den Thillart,Marten Boetzer,Walter Pirovano,Ron P. Dirks,Herman P. Spaink,Denis Duboule,Edwina McGlinn,R. Manjunatha Kini,Michael K. Richardson +41 more
TL;DR: It is shown that regulatory components of the venom secretory system may have evolved from a pancreatic origin and that venom toxin genes were co-opted by distinct genomic mechanisms, which provides insight into mechanisms of protein evolution under strong selection.
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Gene expression profiling of the long-term adaptive response to hypoxia in the gills of adult zebrafish.
David L. M. van der Meer,Guido van den Thillart,Frans Witte,Merijn A. G. de Bakker,Jaya Besser,Michael K. Richardson,Herman P. Spaink,Jelani T. D. Leito,Christoph P. Bagowski +8 more
TL;DR: A novel adaptive mechanism to hypoxia is suggested, the induction of genes for lysosomal lipid trafficking and degradation, which may have important clinical implications in species tolerant for extremely low oxygen levels.
Journal ArticleDOI
Eel migration to the Sargasso: remarkably high swimming efficiency and low energy costs
Vincent van Ginneken,E. Antonissen,Ulrike K. Müller,Ronald Booms,Ep H. Eding,Johan A.J. Verreth,Guido van den Thillart +6 more
TL;DR: It is found that eels swim 4–6 times more efficiently than non-eel-like fish, removing a central objection to Schmidt's theory by showing that their energy reserves are, in principle, sufficient for the migration.
Journal ArticleDOI
The effects of cortisol administration on intermediary metabolism in teleost fish
TL;DR: This Mini Review deals with the metabolic consequences of administration of the hormone cortisol on proteins, carbohydrates and lipids in teleost fish and shows that some effects are inconsistent.
Journal ArticleDOI
Primitive duplicate Hox clusters in the European eel's genome.
Christiaan V. Henkel,Erik Burgerhout,Daniëlle L. de Wijze,Ron P. Dirks,Yuki Minegishi,Hans J. Jansen,Herman P. Spaink,Sylvie Dufour,Finn-Arne Weltzien,Katsumi Tsukamoto,Guido van den Thillart +10 more
TL;DR: It is shown that unlike any other teleost fish, the eel retains fully populated, duplicate Hox clusters, which originated at the teleost-specific genome duplication, and all copies are expressed in early embryos.