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Guixia Yu
Researcher at University of California, San Francisco
Publications - 44
Citations - 8309
Guixia Yu is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Gene & Zika virus. The author has an hindex of 24, co-authored 40 publications receiving 6058 citations. Previous affiliations of Guixia Yu include Cornell University.
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Rapid Detection of 2019 Novel Coronavirus SARS-CoV-2 Using a CRISPR-based DETECTR Lateral Flow Assay
James Paul Broughton,Xianding Deng,Guixia Yu,Clare L Fasching,Jasmeet Singh,Jessica Streithorst,Andrea Granados,Alicia Sotomayor-Gonzalez,Kelsey C. Zorn,Allan Gopez,Elaine Hsu,Wei Gu,Steven P. Miller,Chao-Yang Pan,Hugo Guevara,Debra A. Wadford,Janice Chen,Charles Y. Chiu +17 more
TL;DR: The development of SARS-CoV-2 DETECTR is reported, a rapid (~30 min), low-cost, and accurate CRISPR-Cas12 based lateral flow assay for detection of SARs-CoVs, and it is demonstrated comparable performance to the US CDC Sars-Cov-2 real-time RT-PCR assay.
Journal ArticleDOI
Idiopathic pneumonia syndrome after hematopoietic cell transplantation: evidence of occult infectious etiologies
Sachiko Seo,Christian Renaud,Jane Kuypers,Jane Kuypers,Charles Y. Chiu,Meei Li Huang,Meei Li Huang,Erik Samayoa,Hu Xie,Guixia Yu,Cynthia E. Fisher,Ted Gooley,Steven P. Miller,Robert C. Hackman,Robert C. Hackman,David Myerson,David Myerson,Ruth Hall Sedlak,Yae Jean Kim,Takahiro Fukuda,David N. Fredricks,David K. Madtes,Keith R. Jerome,Keith R. Jerome,Michael Boeckh +24 more
TL;DR: It was demonstrated that approximately half of patients with IPS had pathogens detected in BAL, and pathogen detection was associated with increased mortality, indicating that an expanded infection detection panel can significantly increase the diagnostic precision for idiopathic pneumonia.
Journal ArticleDOI
Metagenomic sequencing with spiked primer enrichment for viral diagnostics and genomic surveillance
Xianding Deng,Asmeeta Achari,Scot Federman,Guixia Yu,Sneha Somasekar,Inês Bártolo,Shigeo Yagi,Placide Mbala-Kingebeni,Jimmy Kapetshi,Steve Ahuka-Mundeke,Jean-Jacques Muyembe-Tamfum,Asim A. Ahmed,Asim A. Ahmed,Vijay S. Ganesh,Manasi Tamhankar,Jean L. Patterson,Nicaise Ndembi,Dora Mbanya,Dora Mbanya,Lazare Kaptue,Carole McArthur,José Esteban Muñoz-Medina,César González-Bonilla,Susana López,Carlos F. Arias,Shaun Arevalo,Steve Miller,Mars Stone,Michael P. Busch,Kristina Hsieh,Sharon Messenger,Debra A. Wadford,Mary A. Rodgers,Gavin Cloherty,Nuno R. Faria,Julien Thézé,Oliver G. Pybus,Zoraima Neto,Joana Morais,Nuno Taveira,John R. Hackett,Charles Y. Chiu +41 more
TL;DR: A new method is described that improves the sensitivity of viral detection compared with next-generation sequencing and enables the detection of emerging flaviviruses not specifically targeted a priori.
Journal ArticleDOI
Genomic Epidemiology Reconstructs the Introduction and Spread of Zika Virus in Central America and Mexico
Julien Thézé,Tony Li,Louis du Plessis,Jerome Bouquet,Moritz U. G. Kraemer,Moritz U. G. Kraemer,Sneha Somasekar,Guixia Yu,Mariateresa de Cesare,Angel Balmaseda,Guillermina Kuan,Eva Harris,Chieh-Hsi Wu,M. Azim Ansari,Rory Bowden,Nuno R. Faria,Shigeo Yagi,Sharon Messenger,Trevor Brooks,Mars Stone,Evan M. Bloch,Michael P. Busch,José Esteban Muñoz-Medina,César González-Bonilla,Steven M. Wolinsky,Susana López,Carlos F. Arias,David Bonsall,Charles Y. Chiu,Oliver G. Pybus +29 more
TL;DR: Multiple lines of evidence indicate biannual peaks of ZIKV transmission in the region, likely driven by varying local environmental conditions for mosquito vectors and herd immunity and challenges arbovirus surveillance and disease control measures.
Journal ArticleDOI
Neurobrucellosis: Unexpected Answer From Metagenomic Next-Generation Sequencing.
Kanokporn Mongkolrattanothai,Samia N. Naccache,Samia N. Naccache,Jeffrey M. Bender,Erik Samayoa,Elizabeth Pham,Guixia Yu,Jennifer Dien Bard,Steve Miller,Grace M. Aldrovandi,Charles Y. Chiu +10 more
TL;DR: The use of a metagenomic next- generation sequencing assay is presented to diagnose a case of neurobrucellosis from cerebrospinal fluid, resulting in the institution of appropriate antibiotic treatment and a favorable clinical outcome.