G
Guiyi Gong
Researcher at University of Macau
Publications - 10
Citations - 196
Guiyi Gong is an academic researcher from University of Macau. The author has contributed to research in topics: Zebrafish & Gene. The author has an hindex of 5, co-authored 8 publications receiving 132 citations. Previous affiliations of Guiyi Gong include Southern University of Science and Technology.
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Journal ArticleDOI
pH-Responsive prodrug nanoparticles based on a sodium alginate derivative for selective co-release of doxorubicin and curcumin into tumor cells
Cheng Gao,Fan Tang,Guiyi Gong,Jianxiang Zhang,Maggie Pui Man Hoi,Simon Ming-Yuen Lee,Ruibing Wang +6 more
TL;DR: It is demonstrated that this novel pH-sensitive prodrug-nanoparticle system may provide a simple and efficient platform for the selective co-delivery of multiple drugs to tumor cells.
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Cardiotoxicity of forchlorfenuron (CPPU) in zebrafish (Danio rerio) and H9c2 cardiomyocytes
TL;DR: This study has identified the cardiotoxicity ofCPPU in different experimental models and enhanced the understanding on the mechanism underlying the toxicity of CPPU to living organisms.
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Rhodol Derivatives as Selective Fluorescent Probes for the Detection of HgII Ions and the Bioimaging of Hypochlorous Acid
TL;DR: With good functionality at physiological pH, probe 2 was successfully used to image HClO in HeLa cells, and high selectivity and sensitivity towards the hypochlorite ion were anticipated, owing to the stoichiometric and irreversible formation of a thiosemicarbazide group.
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A Novel ShK-Like Toxic Peptide from the Transcriptome of the Cnidarian Palythoa caribaeorum Displays Neuroprotection and Cardioprotection in Zebrafish
Qiwen Liao,Guiyi Gong,Shirley W. I. Siu,Clarence T. T. Wong,Huidong Yu,Yu Chung Tse,Gandhi Rádis-Baptista,Simon Ming-Yuen Lee +7 more
TL;DR: The present results indicated that PcShK3 is a novel member of ShK toxin family, and has the intrinsic ability to induce neuro- and cardio-protective effects or cause cardiac toxicity, according to its effective concentration.
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In Vivo Screening of Xanthones from Garcinia oligantha Identified Oliganthin H as a Novel Natural Inhibitor of Convulsions
Guiyi Gong,Guiyi Gong,Han-Bin Chen,Hiotong Kam,Ging Chan,Yue-Xun Tang,Man Wu,Hongsheng Tan,Yu-Chung Tse,Hong-Xi Xu,Simon Ming-Yuen Lee +10 more
TL;DR: The findings present the anticonvulsant activity of oliganthin H, provide a novel scaffold for further modifications, and highlight the xanthone skeleton as an attractive and reliable resource for the development of emerging AEDs.