G
Gulia Babadjanova
Publications - 3
Citations - 233
Gulia Babadjanova is an academic researcher. The author has contributed to research in topics: Single-nucleotide polymorphism & Genome-wide association study. The author has an hindex of 3, co-authored 3 publications receiving 212 citations.
Papers
More filters
Journal ArticleDOI
Brain-specific tryptophan hydroxylase 2 (TPH2): a functional Pro206Ser substitution and variation in the 5′-region are associated with bipolar affective disorder
Sven Cichon,Ingeborg Winge,Manuel Mattheisen,Alexander Georgi,A. Karpushova,Jan Freudenberg,Yun Freudenberg-Hua,Gulia Babadjanova,Ann Van Den Bogaert,Lilia I. Abramova,Sofia Kapiletti,Per M. Knappskog,Jeffrey A. McKinney,Wolfgang Maier,Rami Abou Jamra,Thomas G. Schulze,Johannes Schumacher,Peter Propping,Marcella Rietschel,Jan Haavik,Markus M. Nöthen +20 more
TL;DR: Examination of the functional effects of TPH2 Pro206Ser provided evidence for a reduced thermal stability and solubility of the mutated enzyme, suggesting reduced 5-HT production in the brain as a pathophysiological mechanism in BPAD.
Journal ArticleDOI
Genome-wide analysis implicates microRNAs and their target genes in the development of bipolar disorder
Andreas J. Forstner,Andreas Hofmann,Anna Maaser,Simon Sumer,Sharof Khudayberdiev,Thomas W. Mühleisen,Thomas W. Mühleisen,Markus Leber,Thomas G. Schulze,Jana Strohmaier,Franziska Degenhardt,Jens Treutlein,Manuel Mattheisen,Manuel Mattheisen,Johannes Schumacher,René Breuer,Susanne Meier,Susanne Meier,Stefan Herms,Stefan Herms,Peter Hoffmann,André Lacour,Stephanie H. Witt,Andreas Reif,Bertram Müller-Myhsok,Bertram Müller-Myhsok,Susanne Lucae,W. Maier,M.P. Schwarz,Helmut Vedder,Jutta Kammerer-Ciernioch,Andrea Pfennig,Michael Bauer,Martin Hautzinger,Susanne Moebus,Lutz Priebe,Sugirthan Sivalingam,A Verhaert,Henning G. Schulz,Piotr M. Czerski,Joanna Hauser,Jolanta Lissowska,Neonilia Szeszenia-Dabrowska,Paul Brennan,James D. McKay,Adam Wright,Adam Wright,Philip B. Mitchell,Philip B. Mitchell,Janice M. Fullerton,Janice M. Fullerton,Peter R. Schofield,Peter R. Schofield,Grant W. Montgomery,S. E. Medland,Scott D. Gordon,Nicholas G. Martin,Valery Krasnov,Alexander Chuchalin,Gulia Babadjanova,Galina Pantelejeva,Lilia I. Abramova,Alexander S. Tiganov,Alexey Polonikov,Elza Khusnutdinova,Elza Khusnutdinova,Martin Alda,Martin Alda,Cristiana Cruceanu,Cristiana Cruceanu,Guy A. Rouleau,Gustavo Turecki,Catherine Laprise,Fabio Rivas,Fermín Mayoral,Manolis Kogevinas,M Grigoroiu-Serbanescu,Peter Propping,Tim Becker,Tim Becker,Marcella Rietschel,Sven Cichon,Gerhard Schratt,Markus M. Nöthen +83 more
TL;DR: In this article, gene-based analyses were performed for all known autosomal microRNAs using the largest genome-wide association data set of bipolar disorder to date (9747 patients and 14278 controls).
Journal ArticleDOI
Variation in P2RX7 candidate gene (rs2230912) is not associated with bipolar I disorder and unipolar major depression in four European samples.
Maria Grigoroiu-Serbanescu,Stefan Herms,Thomas W. Mühleisen,Alexander Georgi,Carmen C. Diaconu,Jana Strohmaier,Piotr M. Czerski,Joanna Hauser,Anna Leszczynska-Rodziewicz,Rami Abou Jamra,Gulia Babadjanova,Alexander S. Tiganov,Valery Krasnov,Sofia Kapiletti,Ana Iulia Neagu,Jennifer Vollmer,René Breuer,Marcella Rietschel,Markus M. Nöthen,Sven Cichon,Peter Propping +20 more
TL;DR: The SNP rs2230912 (P2RX7‐E13A) resulting in a change of the amino acid glutamine to arginine at position 460 (Gln460Arg) was replicated in four European bipolar I disorder samples from Germany, Poland, Romania, and Russia totaling 1,445 patients.