G
Gülin Öz
Researcher at University of Minnesota
Publications - 125
Citations - 5582
Gülin Öz is an academic researcher from University of Minnesota. The author has contributed to research in topics: Spinocerebellar ataxia & Neurochemical. The author has an hindex of 38, co-authored 110 publications receiving 4355 citations.
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Journal ArticleDOI
Animal models and high field imaging and spectroscopy
Gülin Öz,Ivan Tkáč,Kamil Ugurbil +2 more
TL;DR: Today, animal model studies are starting to be conducted at magnetic fields ranging from ~ 11 to 17 Tesla, significantly enhancing the armamentarium of tools available for the probing brain function and brain pathologies.
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In Vivo Molecular Signatures of Cerebellar Pathology in Spinocerebellar Ataxia Type 3.
Maria do Carmo Costa,Maria Radzwion,Hayley S. McLoughlin,Naila S. Ashraf,Svetlana Fischer,Vikram G. Shakkottai,Patrícia Maciel,Henry L. Paulson,Gülin Öz +8 more
TL;DR: No treatment exists for the most common dominantly inherited ataxia Machado‐Joseph disease, or spinocerebellar ataxian type 3 (SCA3), and evaluation of candidate therapeutics will be facilitated by validated noninvasive biomarkers of disease pathology recapitulated by animal models.
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Initial experience with seven tesla magnetic resonance spectroscopy of hypothalamic GABA during hyperinsulinemic euglycemia and hypoglycemia in healthy humans
Amir Moheet,Uzay E. Emir,Melissa Terpstra,Anjali Kumar,Lynn E. Eberly,Elizabeth R. Seaquist,Gülin Öz +6 more
TL;DR: To investigate the feasibility of measuring GABA in the hypothalamus in humans, ultra‐high field MRS was used.
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Sensitivity of Volumetric Magnetic Resonance Imaging and Magnetic Resonance Spectroscopy to Progression of Spinocerebellar Ataxia Type 1.
Dinesh K. Deelchand,James M. Joers,Adarsh Ravishankar,Tianmeng Lyu,Uzay E. Emir,Diane Hutter,Christopher M. Gomez,Khalaf Bushara,Christophe Lenglet,Lynn E. Eberly,Gülin Öz +10 more
TL;DR: Volumetric magnetic resonance imaging (MRI) was shown to be more sensitive to disease progression than the most sensitive clinical measure, the Scale for the Assessment and Rating of Ataxia (SARA), in longitudinal studies, and magnetic resonance spectroscopy (MRS) was shows to detect neurochemical abnormalities with high sensitivity cross‐sectionally in SCA1.
Journal ArticleDOI
Assessment of Cerebral and Cerebellar White Matter Microstructure in Spinocerebellar Ataxias 1, 2, 3, and 6 Using Diffusion MRI.
Young W. Park,James M. Joers,Bin Guo,Diane Hutter,Khalaf Bushara,Isaac M. Adanyeguh,Lynn E. Eberly,Gülin Öz,Christophe Lenglet +8 more
TL;DR: In this article, a longitudinal analysis of dMRI data in spinocerebellar ataxia (SCA) patients was performed using three different pipelines: region of interest (ROI), tract-based spatial statistics (TBSS), and fixel-based analysis (FBA).