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Gustavo Costa

Researcher at University of Coimbra

Publications -  25
Citations -  864

Gustavo Costa is an academic researcher from University of Coimbra. The author has contributed to research in topics: Cymbopogon citratus & Luteolin. The author has an hindex of 16, co-authored 25 publications receiving 685 citations.

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Propolis and its constituent caffeic acid suppress LPS-stimulated pro-inflammatory response by blocking NF-κB and MAPK activation in macrophages

TL;DR: Propolis exerted an antioxidant and anti-inflammatory action and caffeic acid may be involved in its inhibitory effects on NO production and intracellular signaling cascades, suggesting its use as a natural source of safe anti- inflammatory drugs.
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Intracellular signaling pathways modulated by phenolic compounds: application for new anti-inflammatory drugs discovery.

TL;DR: It is established that the structure-activity relationships of phenolic compounds are a valuable information source on the development of new anti-inflammatory drugs from natural products.
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Chemical characterization and anti- inflammatory activity of luteolin glycosides isolated from lemongrass

TL;DR: In this paper, the cassia-occidentalin B structure of luteolin and its glycosides was characterized in lemongrass infusion. And the anti-inflammatory activity of Luteolin was evaluated in lipopolysaccharide-stimulated macrophages.
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Urtica spp.: Phenolic composition, safety, antioxidant and anti-inflammatory activities.

TL;DR: Interestingly, statin-like compounds detected in Urtica membranacea have been associated with hypocholesterolemic activity making this plant interesting for future investigations, suggesting their safety use in food applications.