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Paulo Pereira

Researcher at Universidade Nova de Lisboa

Publications -  118
Citations -  9174

Paulo Pereira is an academic researcher from Universidade Nova de Lisboa. The author has contributed to research in topics: Proteasome & Ubiquitin. The author has an hindex of 37, co-authored 107 publications receiving 8213 citations. Previous affiliations of Paulo Pereira include University of Coimbra & National University of Singapore.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Methylglyoxal promotes oxidative stress and endothelial dysfunction

Cristina M. Sena, +6 more
- 01 May 2012 - 
TL;DR: Evidence is provided for methylglyoxal as one of the causative factors in the pathogenesis of atherosclerosis and development of macrovascular diabetic complication by increasing oxidative stress and/or AGEs formation with a concomitant increment of inflammation and a decrement in NO bioavailability.
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Exosomes secreted by cardiomyocytes subjected to ischaemia promote cardiac angiogenesis.

Teresa Ribeiro-Rodrigues, +20 more
- 01 Sep 2017 - 
TL;DR: It is established that exosomes secreted by cardiomyocytes under ischaemic conditions promote heart angiogenesis, which may pave the way towards the development of add-on therapies to enhance myocardial blood supply.
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STUB1/CHIP is required for HIF1A degradation by chaperone-mediated autophagy.

Joao Vasco Ferreira, +6 more
- 07 Jun 2013 - 
TL;DR: This study shows that the KFERQ-like motif, that has been identified in all CMA substrates, is required to mediate the interaction between Hif1A and the chaperone HSPA8, and shows for the first time that the ubiquitin ligase STUB1 is required for degradation of HIF1A in the lysosome by CMA.
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Gap junctional protein Cx43 is involved in the communication between extracellular vesicles and mammalian cells

Ana Soares, +11 more
- 19 Aug 2015 - 
TL;DR: It is shown that Connexin 43 (Cx43), the most widely expressed GJ protein, is present in exosomes in the form of hexameric channels and, more importantly, that exosomal Cx43 is able to modulate the interaction and transfer of information between exosome and acceptor cells.