H
H.-J. Galla
Researcher at University of Münster
Publications - 7
Citations - 897
H.-J. Galla is an academic researcher from University of Münster. The author has contributed to research in topics: Binding constant & Monolayer. The author has an hindex of 7, co-authored 7 publications receiving 742 citations.
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Journal ArticleDOI
In vitro models of the blood-brain barrier: An overview of commonly used brain endothelial cell culture models and guidelines for their use
Hans Christian Cederberg Helms,N. Joan Abbott,Malgorzata Burek,Roméo Cecchelli,Pierre Olivier Couraud,Mária A. Deli,Carola Förster,H.-J. Galla,Ignacio A. Romero,Eric V. Shusta,Matthew J. Stebbins,Elodie Vandenhaute,Babette B. Weksler,Birger Brodin +13 more
TL;DR: A review of established in vitro blood-brain barrier models with a focus on their validation regarding a set of well-established bloodbrain barrier characteristics is given in this paper, with an overview of the advantages and drawbacks of the different models described.
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Double-mode impedance analysis of epithelial cell monolayers cultured on shear wave resonators.
TL;DR: The presence of a cell-layer mainly increases damping of the shear wave and does not exhibit a pure mass-load behavior, supported by the discovery that the inductance L in the electromechanical model was less influenced by the cell- layer than the resistance R.
Journal Article
Porcine choroid plexus cells in culture: expression of polarized phenotype, maintenance of barrier properties and apical secretion of CSF-components.
TL;DR: The cells in culture secrete medium containing prealbumin predominantly into the apical compartment which demonstrates that they are able to release medium containing CSF-proteins and therefore verifies the usefulness of this in vitro model.
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Quartz crystal microbalance investigation of the interaction of bacterial toxins with ganglioside containing solid supported membranes.
Andreas Janshoff,Claudia Steinem,Manfred Sieber,A. el Bayâ,Marcus Alexander Schmidt,H.-J. Galla +5 more
TL;DR: The maximum frequency shift caused by the protein adsorption depends strongly on the molecular structure of the receptor, which is clearly demonstrated by an observed maximum frequency decrease of 99 Hz for the Adsorption of the C-fragment of tetanus toxin to GD1b.
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Kinetics of phospholipid insertion into monolayers containing the lung surfactant proteins SP-B or SP-C
TL;DR: It is proposed that the preferential interaction between SP-B and negatively charged DPPG leads to accumulation of negative charges in particular regions, causing strong adhesion between DPPG-containing vesicles and the monolayer mediated by Ca2+ ions, which eventually causes flattening and rupture of attached liposomes as observed by in situ SFM.