H
H.-P. Horny
Researcher at Ludwig Maximilian University of Munich
Publications - 23
Citations - 846
H.-P. Horny is an academic researcher from Ludwig Maximilian University of Munich. The author has contributed to research in topics: Systemic mastocytosis & Mast cell leukemia. The author has an hindex of 13, co-authored 23 publications receiving 723 citations.
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Journal ArticleDOI
Proposed diagnostic algorithm for patients with suspected mastocytosis: a proposal of the European Competence Network on Mastocytosis
Peter Valent,Luis Escribano,Sigurd Broesby-Olsen,Karin Hartmann,Clive Grattan,Knut Brockow,Marek Niedoszytko,Bogusław Nedoszytko,J. N. G. Oude Elberink,Thomas Kielsgaard Kristensen,Joseph H. Butterfield,Massimo Triggiani,Iván Álvarez-Twose,Andreas Reiter,Wolfgang R. Sperr,Karl Sotlar,Selim Yavuz,Hanneke C. Kluin-Nelemans,Olivier Hermine,Deepti Radia,J. J. Van Doormaal,Jason Gotlib,A. Orfao,Frank Siebenhaar,Lawrence B. Schwartz,Mariana Castells,Marcus Maurer,H.-P. Horny,Cem Akin,Dean D. Metcalfe,Michel Arock +30 more
TL;DR: A diagnostic algorithm is developed that will facilitate the management of patients with suspected mastocytosis and help avoid unnecessary referrals and investigations.
Journal ArticleDOI
Molecular profiling of myeloid progenitor cells in multi-mutated advanced systemic mastocytosis identifies KIT D816V as a distinct and late event
Mohamad Jawhar,Juliana Schwaab,Susanne Schnittger,Karl Sotlar,H.-P. Horny,Georgia Metzgeroth,Nadine Muller,Stephanie Schneider,Nicole Naumann,Christoph Walz,T Haferlach,Peter Valent,W.-K. Hofmann,Nicholas C.P. Cross,Alice Fabarius,Andreas Reiter +15 more
TL;DR: Data indicate that SM-AHNMD is a multi-mutated neoplasm, KIT D816V or other mutations are rare in CFU-GM colonies of ISM/SSM patients, which might explain at least in part their better prognosis.
Journal ArticleDOI
Predictors of clinical effectiveness of Hymenoptera venom immunotherapy.
Franziska Ruëff,Byrthe J. P. R. Vos,Byrthe J. P. R. Vos,J. N. G. Oude Elberink,Andreas Bender,R. Chatelain,R. Chatelain,Susanne Dugas-Breit,H.-P. Horny,Helmut Küchenhoff,A. Linhardt,Sebastian Mastnik,Karl Sotlar,E. Stretz,R. Vollrath,Bernhard Przybilla,Michael J. Flaig +16 more
TL;DR: Treatment failure during venom immunotherapy (VIT) may be associated with a variety of risk factors, of which the relative importance is unknown.
Journal ArticleDOI
Refined diagnostic criteria and classification of mast cell leukemia (MCL) and myelomastocytic leukemia (MML): a consensus proposal
Peter Valent,Karl Sotlar,Wolfgang R. Sperr,Luis Escribano,Selim Yavuz,Andreas Reiter,Tracy I. George,Hanneke C. Kluin-Nelemans,Olivier Hermine,Joseph H. Butterfield,Hans Hägglund,Celalettin Ustun,Jason L. Hornick,Massimo Triggiani,Deepti Radia,Cem Akin,Karin Hartmann,Jason Gotlib,Lawrence B. Schwartz,Srdan Verstovsek,A. Orfao,Dean D. Metcalfe,Michel Arock,H.-P. Horny +23 more
TL;DR: The refined classification of MCL fits within and extends the current WHO classification; and should improve prognostication and patient selection in practice as well as in clinical trials.
Journal ArticleDOI
Detection of c-kit mutation Asp 816 to Val in microdissected bone marrow infiltrates in a case of systemic mastocytosis associated with chronic myelomonocytic leukaemia.
Karl Sotlar,Teresa Marafioti,H Griesser,J Theil,C Aepinus,R Jaussi,Harald Stein,Peter Valent,H.-P. Horny +8 more
TL;DR: The data support a monoclonal evolution of systemic mastocytosis and concurrent CMML in the patient studied, and no c-kit mutation Asp 816 to Val was found in bone marrow infiltrates in patients with CMML without associated systemic mastocytes.