H
H. R. P. Miller
Researcher at University of Edinburgh
Publications - 5
Citations - 288
H. R. P. Miller is an academic researcher from University of Edinburgh. The author has contributed to research in topics: Mast cell & Thioperamide. The author has an hindex of 5, co-authored 5 publications receiving 276 citations.
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Journal ArticleDOI
Functional relationship between mast cells and C-sensitive nerve fibres evidenced by histamine H3-receptor modulation in rat lung and spleen
V. Dimitriadou,A. Rouleau,M. Dam Trung Tuong,G. J. F. Newlands,H. R. P. Miller,G. Luffau,J.-C. Schwartz,Monique Garbarg +7 more
TL;DR: It is concluded that the control of mast cells by histamine acting at H3-receptors involves neuropeptide-containing nerves and presumably reflects the operation of a local neuron-mast cell feedback loop controlling processes such as 'neurogenic inflammation'.
Journal ArticleDOI
Functional relationships between sensory nerve fibers and mast cells of dura mater in normal and inflammatory conditions
V. Dimitriadou,A. Rouleau,M.D. Trung Tuong,G. J. F. Newlands,H. R. P. Miller,G. Luffau,J.-C. Schwartz,Monique Garbarg +7 more
TL;DR: In the dura mater, as in peripheral tissues, sensory nerve fibers and mast cells actively synthesizing and releasing histamine form a short inhibitory feedback loop involving prejunctional H3 receptors that could regulate the release of pro-inflammatory mediators, thus limiting the extent of inflammatory reactions.
Journal ArticleDOI
Rat cerebral mast cells undergo phenotypic changes during development
V. Dimitriadou,A. Rouleau,M.D. Trung Tuong,X. Ligneau,G. F. J. Newlands,H. R. P. Miller,J.-C. Schwartz,Monique Garbarg +7 more
TL;DR: This study shows that in the adult, both types of mast cells are present, although in small numbers, except for RMCP-I-immunoreactive mast cells which are abundant in the thalamus of adult rats.
Journal ArticleDOI
Mast cell specific proteases in rat brain: changes in rats with experimental allergic encephalomyelitis.
A. Rouleau,V. Dimitriadou,M.D. Trung Tuong,G. F. J. Newlands,H. R. P. Miller,J.-C. Schwartz,Monique Garbarg +6 more
TL;DR: The cerebral RMCPII-expressing mast cells could play a role during EAE, and the markers of histaminergic neurons were marginally affected 13 days after immunisation.
Journal ArticleDOI
Fasting or dexamethasone treatment reduce protease content in rat lung mast cells and modulation of histamine synthesis by H3 receptors.
A. Rouleau,M. Dam Trung Tuong,G. F. J. Newlands,H. R. P. Miller,J.-C. Schwartz,Monique Garbarg +5 more
TL;DR: A subpopulation of RMCP II-containing mast cells, very sensitive to environmental factors, could be the mast cells synthesizing HA in an H3-receptor-dependant manner.