H
Haiying Zhu
Researcher at University of Washington
Publications - 17
Citations - 512
Haiying Zhu is an academic researcher from University of Washington. The author has contributed to research in topics: Viral replication & Viral load. The author has an hindex of 8, co-authored 17 publications receiving 344 citations. Previous affiliations of Haiying Zhu include University of Washington Medical Center.
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Journal ArticleDOI
Case of Yellow Fever Vaccine-associated Viscerotropic Disease with Prolonged Viremia, Robust Adaptive Immune Responses, and Polymorphisms in CCR5 and RANTES Genes
Bali Pulendran,Joseph I. Miller,Joseph I. Miller,Troy D. Querec,Rama Akondy,Nelson B. Moseley,Oskar Laur,John Glidewell,Nathan Monson,Tuofu Zhu,Haiying Zhu,Sylvija Staprans,David Lee,Margo A. Brinton,Andrey A. Perelygin,Claudia J. Vellozzi,Philip Sigmund Brachman,Susan Lalor,Dirk E. Teuwen,Rachel B. Eidex,Martin S. Cetron,Frances Priddy,Carlos del Rio,John D. Altman,Rafi Ahmed +24 more
TL;DR: In this patient, viscerotropic disease was not due to the impaired magnitude of adaptive immunity but instead to anomalies in the innate immune system and a possible disruption of the CCR5-RANTES axis.
Journal ArticleDOI
Env length and N-linked glycosylation following transmission of human immunodeficiency virus Type 1 subtype B viruses.
Yi Liu,Marcel E. Curlin,Kurt Diem,Hong Zhao,Ananta K. Ghosh,Haiying Zhu,Amanda Woodward,Janine Maenza,Claire E. Stevens,Joanne D. Stekler,Ann C. Collier,Indira Genowati,Wenjie Deng,Rafael Zioni,Lawrence Corey,Lawrence Corey,Tuofu Zhu,James I. Mullins +17 more
TL;DR: It is found that during transmission of HIV-1 subtype B, as for other subtypes reported in the past, viral populations in recipients undergo substantial genetic bottlenecks, as well as weak evidence for a propensity to replicate viruses with shorter variable loops and fewer potential N-linked glycosylation sites.
Journal ArticleDOI
Evaluation of cell-based and surrogate SARS-CoV-2 neutralization assays.
Anton M Sholukh,Andrew Fiore-Gartland,Emily S Ford,Maurine D. Miner,Yixuan J. Hou,Longping V. Tse,Hannah Kaiser,Haiying Zhu,Joyce Y C Lu,Bhanupriya Madarampalli,Arnold Park,Florian A. Lempp,Russell St Germain,Emily L Bossard,Jia Jin Kee,Kurt Diem,Andrew B. Stuart,Peter B. Rupert,Chance Brock,Matthew Buerger,Margaret K. Doll,April K. Randhawa,Leonidas Stamatatos,Roland K. Strong,Colleen McLaughlin,Meei-Li Huang,Keith R. Jerome,Keith R. Jerome,Ralph S. Baric,David C. Montefiori,Lawrence Corey,Lawrence Corey +31 more
TL;DR: Head-to-head evaluation of different SARS-CoV-2 neutralization platforms could facilitate comparisons across studies and laboratories, and high concordance between the outcomes of cell-based assays with live and pseudotyped virions enables valid cross-study comparison using these platforms.
Journal ArticleDOI
Anti-SARS-CoV-2 Antibody Levels Measured by the AdviseDx SARS-CoV-2 Assay Are Concordant with Previously Available Serologic Assays but Are Not Fully Predictive of Sterilizing Immunity.
Benjamin T. Bradley,Andrew Bryan,Susan L. Fink,Erin A. Goecker,Pavitra Roychoudhury,Meei-Li Huang,Haiying Zhu,Anu Chaudhary,Bhanupriya Madarampalli,Joyce Y C Lu,Kathy Strand,Estella Whimbey,Chloe Bryson-Cahn,Adrienne Schippers,Nandita S Mani,Gregory Pepper,Keith R. Jerome,Keith R. Jerome,Chihiro Morishima,Robert W. Coombs,Mark H. Wener,Seth M. Cohen,Alexander L. Greninger,Alexander L. Greninger +23 more
TL;DR: In this paper, the authors investigated the performance characteristics of the recently FDA-authorized semiquantitative anti-spike protein AdviseDx SARS-CoV-2 IgG II assay compared to the FDA authorized anti-nucleocapsid protein Abbott Architect SARS CoV2 IgG, Roche Elecsys anti-SARS-coV2-S, EuroImmun anti SARSCoV2 enzyme-linked immunosorbent assay (ELISA), and GenScript surrogate virus neutralization assays and examined the humoral response
Journal ArticleDOI
Continued evolution of HIV-1 circulating in blood monocytes with antiretroviral therapy: genetic analysis of HIV-1 in monocytes and CD4+ T cells of patients with discontinued therapy.
Nicholas Llewellyn,Rafael Zioni,Haiying Zhu,Thomas Andrus,Younong Xu,Lawrence Corey,Lawrence Corey,Tuofu Zhu,Tuofu Zhu +8 more
TL;DR: It is suggested that ART inhibits HIV‐1 replication in CD4+ T cells more than in blood monocytes and that better treatments to combat HIV‐ 1 in monocytes/macrophages may be needed for a more complete suppression of HIV replication.