H
Hal E. Broxmeyer
Researcher at Indiana University
Publications - 56
Citations - 12179
Hal E. Broxmeyer is an academic researcher from Indiana University. The author has contributed to research in topics: Stem cell & Bone marrow. The author has an hindex of 26, co-authored 56 publications receiving 11650 citations. Previous affiliations of Hal E. Broxmeyer include University of Texas Health Science Center at Houston & University of Washington.
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Preservation of fetal and neonatal hematopoietic stem and progenitor cells of the blood
TL;DR: In this paper, the use of fetal stem and progenitor cells for hematopoietic reconstitution was discussed, which can be valuable in the treatment or prevention of various diseases and disorders such as anemias, malignancies, autoimmune disorders, and various immune dysfunctions and deficiencies.
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Differentiation of human pluripotent stem cells to cells similar to cord-blood endothelial colony–forming cells
Nutan Prasain,Man Ryul Lee,Sasidhar Vemula,Jonathan Luke Meador,Momoko Yoshimoto,Michael J. Ferkowicz,Alexa Fett,Manav Gupta,Brian M. Rapp,Mohammad Reza Saadatzadeh,Michael Ginsberg,Olivier Elemento,Younghee Lee,Sherry L. Voytik-Harbin,Hyung-Min Chung,Ki Sung Hong,Emma Reid,Christina L. O'Neill,Reinhold J. Medina,Alan W. Stitt,Michael P. Murphy,Shahin Rafii,Hal E. Broxmeyer,Mervin C. Yoder +23 more
TL;DR: A protocol to convert human induced pluripotent stem cells or embryonic stem cells into cells similar to CB-ECFCs at an efficiency of >108 ECFCs produced from each starting pluripotencephalic stem cell is described.
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A noncytotoxic DsRed variant for whole-cell labeling.
Rita Strack,Daniel E. Strongin,Dibyendu Bhattacharyya,Wen Tao,Allison Berman,Hal E. Broxmeyer,Robert J. Keenan,Benjamin S. Glick +7 more
TL;DR: DsRed-Express2 exhibits strong and stable expression in bacterial and mammalian cells, and it outperforms other available RFPs with regard to photostability and phototoxicity.
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Glucocorticoid hormone-induced chromatin remodeling enhances human hematopoietic stem cell homing and engraftment.
TL;DR: Glucocorticoid hormone signaling is identified as an activator of CXCR4 expression in human CB HSCs and hematopoietic progenitor cells (HPCs) and suggested to be a new and readily available means to enhance the clinical efficacy of CB HCT.
Journal Article
Estrogen loss upregulates hematopoiesis in the mouse: a mediating role of IL-6
TL;DR: It is established that, in addition to upregulation of osteoclastogenesis, loss of estrogens in the mouse causes widespread effects on hematopoiesis, which are apparently mediated by IL-6.