Younghee Lee

TL;DR: In this paper, the authors proposed an intermediate state defined by ≤ 5 cumulative metastasis(es), termed oligometastases, which may benefit from metastasis-directed local treatments.

TL;DR: A protocol to convert human induced pluripotent stem cells or embryonic stem cells into cells similar to CB-ECFCs at an efficiency of >108 ECFCs produced from each starting pluripotencephalic stem cell is described.

TL;DR: It is demonstrated for the first time how phenotypic knowledge of inheritable cancer traits and of risk factor loci can be utilized jointly with gene expression analysis to efficiently prioritize deregulated microRNAs for biological characterization and provide improved efficiency in characterization and modeling of microRNA functions in cancer.

TL;DR: The gene-modeling algorithm combines the genome-based expressed sequence tag (EST) clustering and graph-theoretic transcript assembly procedures to infer qualitative expression patterns from SAGE libraries available publically.

TL;DR: It is proposed that intronic SNPs play a role as genetic regulators within splicing regulatory elements and show that their associated exon skipping events can affect protein domains and structure and are enriched among the set of SNPs reported to be associated with complex human traits.