Hala El-Zimaity

TL;DR: In this paper, the authors provide recommendations and opinions of the Canadian Association of Pathologists-Association canadienne des pathologistes National Standards Committee/Immunohistochemistry relevant to clinical immunohistochemical terminology, classification of immuno-istochemical tests based on risk assessment, and quality control and quality assurance and summarizes matters to be considered for appropriate immunoistochemical/immunocytochemical test development, performance and interpretation in diagnostic pathology and laboratory medicine.

TL;DR: This document provides recommendations and opinions of the Canadian Association of Pathologists-Association canadienne des pathologistes National Standards Committee/Immunohistochemistry relevant to clinical immunohistochemical terminology, classification of immunohISTochemical tests based on risk assessment, and quality control and quality assurance and summarizes matters to be considered for appropriate immunohistsochemical/immunocytochemical test development, performance, and interpretation in diagnostic pathology and laboratory medicine.

TL;DR: Colitis associated with PSC shows mild disease activity and the colitis pattern is associated with disease presentation, i.e. colitis preceding PSC typically have a pancolitic distribution, while colitis following PSC (PSC-IBD cohort) demonstrates right-sided predominance.

TL;DR: The objective of this document is to provide evidence-based guidance to assist clinical laboratories in establishing fit-for-purpose PD-L1 biomarker assays that can accurately identify patients with specific tumor types who may respond to specific approved immuno-oncology therapies targeting the PD-1/PD-L 1 checkpoint.

TL;DR: The majority of problems in interpreting gastritis remain Helicobacter related, but their nature has changed and it is now possible to stage patients for cancer risk, so a classification or staging system that is more descriptive will likely prove more useful.